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Brian M Balgley

from Alexandria, VA
Age ~52
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Also known as:
Brian Bagley
Related to:
Kathryn T Casey, 83Annemarie B Reed, 46Annemari Balgley, 45Kim M Gibson, 62Hui C Kim, 80Caroline S Lee, 51Young A Kim, 51Kihwan Kim, 59Yang Ja KimReed Annemarie Bagley, 73Yangja Ja KimJohn U Kim, 53Penelope J Balgley, 82Esther Y Chae, 52Jaekyung Kim Kyung, 67Dohyeong KimJulia Kim, 53Yong Hwan Kim, 88Michael J Balgley, 84Andy Kim, 73Julia E Kim, 50
Connected to:
Bissoondeo Balgobin, 62Christine Balgobin, 38Cindy S Balgobin, 33Michelle M Balgobind, 33Richard W Balgobin, 75Gary R Balgord, 72Gene R Balgos, 55Oliver Balgos, 33Sahil Balgotra, 41Amy C Balgoyen, 55

Brian Balgley Phones & Addresses

  • Alexandria, VA
  • 8300 Apple Ct, Fairfax Station, VA 22039 (703) 999-5622
  • Chantilly, VA
  • 7154 Pennys Town Ct, Annandale, VA 22003
  • 9480 Virginia Center Blvd, Vienna, VA 22181
  • 11238 Cherry Hill Rd, Beltsville, MD 20705
  • New York, NY
  • Lorton, VA
  • Laurel, MD
  • 8300 Apple Ct, Fairfax Station, VA 22039

Work

Company: Bioproximity Jul 2008 Position: Managing partner

Education

Degree: Bachelors, Bachelor of Science School / High School: University of California, Davis

Skills

Mass Spectrometry • Proteomics • Capillary Electrophoresis • Chromatography • Amazon Web Services • Biochemistry • Analytical Biochemistry • Electrophoresis • Hplc • Lc Ms • Protein Chemistry • Biomarker Discovery • Biomarker Development • Lifesciences • Bioinformatics • Genomics • Biotechnology

Industries

Biotechnology

Resumes

Resumes

Brian Balgley Photo 1

Managing Partner

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Location:
4850 Eisenhower Ave, Alexandria, VA 22304
Industry:
Biotechnology
Work:
Bioproximity
Managing Partner
Education:
University of California, Davis
Bachelors, Bachelor of Science University of Maryland
Doctorates, Doctor of Philosophy
Skills:
Mass Spectrometry
Proteomics
Capillary Electrophoresis
Chromatography
Amazon Web Services
Biochemistry
Analytical Biochemistry
Electrophoresis
Hplc
Lc Ms
Protein Chemistry
Biomarker Discovery
Biomarker Development
Lifesciences
Bioinformatics
Genomics
Biotechnology

Business Records

Name / Title
Company / Classification
Phones & Addresses
Brian Balgley
Chief Technology Officer
Calibrant Biosystems Inc
Biotechnology
910 Clopper Rd, Gaithersburg, MD 20878
847 Quince Orch Blvd, Gaithersburg, MD 20878
3823 Grosvenor Dr, Ellicott, MD 21042
(301) 424-2320, (301) 977-7900, (301) 977-7981

Publications

Us Patents

Methods And Systems For Multidimensional Concentration And Separation Of Biomolecules Using Capillary Isotachophoresis

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US Patent:
20080156080, Jul 3, 2008
Filed:
Jan 2, 2007
Appl. No.:
11/619054
Inventors:
Brian M. Balgley - Annandale VA, US
Assignee:
Calibrant Biosystems, Inc. - Rockville MD
International Classification:
G01N 30/02
G01N 21/00
G01N 30/84
G01N 37/00
US Classification:
73 6147, 73 6148, 73 6153, 73 6155
Abstract:
The invention provides a method for performing off-line multi-dimensional separation and analysis of a heterogeneous biomolecular sample. The method includes separating the heterogeneous biomolecular sample into a plurality of fractions using an, at least partially, capillary isotachophoresis mechanism. The plurality of fractions are then transferred to a liquid chromatography apparatus where they are each separated into a plurality of sub-fractions. The sub-fractions are then analyzed to determine their constituent molecules.

Methods And Systems For Off-Line Multidimensional Concentration And Separation Of Biomolecules

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US Patent:
20080160629, Jul 3, 2008
Filed:
Jan 2, 2007
Appl. No.:
11/619041
Inventors:
Brian M. Balgley - Annandale VA, US
Assignee:
Calibrant Biosystems, Inc. - Rockville MD
International Classification:
G01N 30/02
B01D 57/02
US Classification:
436161, 204451, 204455
Abstract:
The invention provides a method for performing off-line multi-dimensional separation and analysis of a heterogeneous biomolecular sample. The method includes separating the heterogeneous biomolecular sample into a plurality of fractions using an electrophoresis capillary. The plurality of fractions are then deposited onto one or more structures, which keep each of the plurality of fractions separate from one another. The plurality of fractions are then subjected to non-eluting conditions by titrating the at least one of the plurality of fractions to an acidic pH and adding an ion-pairing reagent to the fractions. At least one of the fractions is then introduced into a capillary reversed-phase electrophoresis capillary. The fraction is then separated in the capillary into a plurality of sub-fractions based on hydrophobicity of the sub-fractions. The sub-fractions are then analyzed to determine their constituent molecules.

Formalin-Fixed Isotope-Labeled Reference Standards And Methods For Fabrication And Use Thereof

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US Patent:
20120231469, Sep 13, 2012
Filed:
Mar 6, 2012
Appl. No.:
13/413110
Inventors:
Brian M. BALGLEY - Fairfax Station VA, US
Assignee:
BIOPROXIMITY, LLC - Springfield VA
International Classification:
G01N 27/62
C12Q 1/02
US Classification:
435 71, 435 29
Abstract:
One or more cells are labeled with minor stable isotopes, characterized, and preserved for subsequent use as a bio-specimen reference standard. The one or more cells are grown in culture media supplied with minor stable isotopes in concentrations substantially different from normally occurring concentrations, thereby supplanting major stable isotopes that would normally be incorporated into the proteins of the cells. The proteins of the cells are thus labeled by the minor stable isotopes and can be used in proteomic characterization of the cells. The cells are preserved by fixation as a reference standard. Cells of the reference standard are mixed with the sample and subject to mass spectrometry evaluation, whereby the labeled proteins of the reference standard can be used in determining the proteome of the sample.

Devices And Methods For Correlated Analysis Of Multiple Protein Or Peptide Samples

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US Patent:
20060019399, Jan 26, 2006
Filed:
Jul 1, 2005
Appl. No.:
11/171427
Inventors:
Brian Balgley - Annandale VA, US
Jonathan Cooper - Walkersville MD, US
Cheng Lee - Ellicott City MD, US
Donald DeVoe - Bethesda MD, US
International Classification:
G01N 33/00
US Classification:
436086000
Abstract:
Disclosed is a system for performing multiple analyses of protein and/or peptide samples and correlating the results of the analyses. The system comprises a sample inlet, a splitter means, at least two sample delivery capillaries, at least two sample deposition tools, and at least two sample collectors, wherein said splitter means is in fluid communication with the sample inlet and the sample delivery capillaries, and wherein liquid flow entering the splitter means is split into a number of sub-flows equal to the number of sample delivery capillaries. In one preferred embodiment, at least one microenzyme reactor is interfaced to a first sample delivery capillary in order to digest a protein sample within the capillary, while a second sample delivery capillary does not contain a microenzyme reactor, thereby enabling correlated analysis of the same protein sample in digested and undigested form. Methods for performing two or more analyses of protein and/or peptide samples and correlating the results of the analyses are also disclosed.

Formalin-Fixed Isotope-Labeled Reference Standards And Methods For Fabrication And Use Thereof

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US Patent:
20190302123, Oct 3, 2019
Filed:
Jun 3, 2019
Appl. No.:
16/430287
Inventors:
- Springfield VA, US
Brian M. BALGLEY - Fairfax Station VA, US
International Classification:
G01N 33/68
Abstract:
One or more cells are labeled with minor stable isotopes, characterized, and preserved for subsequent use as a bio-specimen reference standard. The one or more cells are grown in culture media supplied with minor stable isotopes in concentrations substantially different from normally occurring concentrations, thereby supplanting major stable isotopes that would normally be incorporated into the proteins of the cells. The proteins of the cells are thus labeled by the minor stable isotopes and can be used in proteomic characterization of the cells. The cells are preserved by fixation as a reference standard. Cells of the reference standard are mixed with the sample and subject to mass spectrometry evaluation, whereby the labeled proteins of the reference standard can be used in determining the proteome of the sample.

Formalin-Fixed Isotope-Labeled Reference Standards And Methods For Fabrication And Use Thereof

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US Patent:
20160334410, Nov 17, 2016
Filed:
May 20, 2016
Appl. No.:
15/159969
Inventors:
- SPRINGFIELD VA, US
Brian M. BALGLEY - Fairfax Station VA, US
International Classification:
G01N 33/68
Abstract:
One or more cells are labeled with minor stable isotopes, characterized, and preserved for subsequent use as a bio-specimen reference standard. The one or more cells are grown in culture media supplied with minor stable isotopes in concentrations substantially different from normally occurring concentrations, thereby supplanting major stable isotopes that would normally be incorporated into the proteins of the cells. The proteins of the cells are thus labeled by the minor stable isotopes and can be used in protcomic characterization of the cells. The cells are preserved by fixation as a reference standard. Cells of the reference standard are mixed with the sample and subject to mass spectrometry evaluation, whereby the labeled proteins of the reference standard can be used in determining the proteome of the sample.
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Brian M Balgley from Alexandria, VA, age ~52 Get Report