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Brendan P Cormack

from Baltimore, MD
Age ~59

Brendan Cormack Phones & Addresses

  • 4304 Wickford Rd, Baltimore, MD 21210 (410) 243-5101
  • 6507 Copper Ridge Dr, Baltimore, MD 21209 (410) 602-3407
  • Santa Cruz, CA
  • Saratoga, CA
  • Brighton, MA
  • Brookline, MA

Resumes

Resumes

Brendan Cormack Photo 1

Professor

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Location:
Baltimore, MD
Industry:
Hospital & Health Care
Work:
Johns Hopkins School of Medicine
Professor
Brendan Cormack Photo 2

Brendan Cormack

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Brendan Cormack Photo 3

Associate Professor At Jhmi

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Position:
Associate Professor at JHMI
Location:
Baltimore, Maryland Area
Industry:
Research
Work:
JHMI
Associate Professor
Education:
Harvard Medical School 1987 - 1993
Ph.D., Genetics

Publications

Us Patents

Leukotriene A4 Hydrolase From Candida Albicans

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US Patent:
55299164, Jun 25, 1996
Filed:
Nov 1, 1994
Appl. No.:
8/332838
Inventors:
Brendan P. Cormack - Saratoga CA
Stanley Falkow - Portola Valley CA
Assignee:
Board of Trustees of the Leland Stanford Junior University - Stanford CA
International Classification:
C12N 914
C12N 1555
US Classification:
435195
Abstract:
The invention relates to yeast leukotriene A. sub. 4 hydrolase enzymes and nucleic acids.

Flourescence-Based Isolation Of Differentially Induced Genes

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US Patent:
59940778, Nov 30, 1999
Filed:
Sep 10, 1997
Appl. No.:
8/926556
Inventors:
Raphael H. Valdivia - Palo Alto CA
Brendan P. Cormack - Santa Cruz CA
Stanley Falkow - Portola Valley CA
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
C12Q 168
C12P 2106
C12P 2104
C12N 902
US Classification:
435 6
Abstract:
Regulatory elements (e. g. promoters) activated by a stimulus are isolated by a FACS-based method. Preferably, a library of random fragments representative of a target (e. g. bacterial) genome are cloned in front of a promoterless gfp (green fluorescent protein) sequence in a plasmid, and inserted into target cells. The resulting target cell mixture is sorted according to GFP levels in the presence and the absence of the stimulus. Suitable stimuli include compounds of interest (e. g. drugs), environmental factors (e. g. extracellular acidity), and complex stimuli such as in vivo environments of hosts infected by the target cells. The method allows identifying pathogen genes which are selectively expressed during infection.

Facs-Optimized Mutants Of The Green Fluorescent Protein (Gfp)

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US Patent:
60909196, Jul 18, 2000
Filed:
Aug 17, 1998
Appl. No.:
9/135418
Inventors:
Brendan P. Cormack - Santa Cruz CA
Raphael H. Valdivia - Palo Alto CA
Stanley Falkow - Portola Valley CA
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
C07K 100
C07H 2102
US Classification:
530350
Abstract:
Three classes of GFP mutants having single excitation maxima around 488 nm are brighter than wild-type GFP following 488 nm excitation. GFPmut1 has a double substitution: F64L, S65T; GFPmut2 has a triple substitution: S65A, V68L, S72A; and GFPmut3 is characterized by the double substitution S65G, S72A. The excitation maxima of the three mutants are at 488 nm, 481 nm and 501 nm respectively. The fluorescence intensities following excitation at 488 nm are an order of magnitude higher than that of wild-type GFP excited at 488 nm in E. coli. The expression of GFP is observable minutes after induction.

Facs-Optimized Mutants Of The Green Fluorescent Protein (Gfp)

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US Patent:
58043870, Sep 8, 1998
Filed:
Jan 31, 1997
Appl. No.:
8/791332
Inventors:
Brendan P. Cormack - Santa Cruz CA
Raphael H. Valdivia - Palo Alto CA
Stanley Falkow - Porola Valley CA
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
C12Q 168
C07H 2102
C12N 120
C12N 500
US Classification:
435 6
Abstract:
Three classes of GFP mutants having single excitation maxima around 488 nm are brighter than lid-type GFP following 488 nm excitation. GFPmut1 has a double substitution: F64L, S65T; GFPmut2 has a triple substitution: S65A, V68L, S72A; and GFPmut3 is characterized by the double substitution S65G, S72A. The excitation maxima of the three mutants are at 488 nm, 481 nm and 501 nm respectively. The fluorescence intensities following excitation at 488 nm are an order of magnitude higher than that of wild-type GFP excited at 488 nm in E. coli. The expression of GFP is observable minutes after induction.
Brendan P Cormack from Baltimore, MD, age ~59 Get Report