Inventors:
Suzanne R. Ellenberger - Salem UT
Galen D. Peiser - Cupertino CA
Russell N. Bell - Salt Lake City UT
Charles E. Hussey - Salt Lake City UT
Bradley D. Swedlund - Salt Lake City UT
Assignee:
Agridyne Technologies, Inc. - Salt Lake City UT
International Classification:
C12N 910
C12N 1554
Abstract:
This invention provides a purified chrysanthemyl diphosphate synthase (CDS), a method for the purification of CDS from Chrysanthemum cinerariaefolium, and an amino acid sequence of the isolated CDS. Also provided is a cDNA encoding the CDS, a nucleotide sequence of the CDS gene, and a derived amino acid sequence of the encoded CDS protein. The CDS gene is useful in the enzymatic production of the natural stereospecific configuration of chrysanthemyl derivatives which are useful for the synthesis of pyrethrins, pyrethroids, derivatives thereof, as well as other classes of metabolites.