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Boris Living Rubinsky

from El Cerrito, CA
Age ~76
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Also known as:
Boris Stefania Rubinsky, Boris R Rubinsky, Boris S Rubinsky, Bons Rubinsky, Boriss Rubinsky, Smadar Rubinsky, Boris Rubinski, Boris Robinsky
Phone and address:
937 Contra Costa Dr, Richmond, CA 94530
Related to:
Meytal Rubinsky, 46Liel RubinskyDan Rubinsky, 47Mary K Meunier, 27Eugene E Meunier, 34Anna F Debenedetti, 44Smadar RubinskyEugent Meunier, 62Stefania Rubinsky, 76Daniel RubinskyEugene E MeunierJonathan Rubinsky, 42Eugene E Meunier, 58Sarah J Meunier, 62Smadar Rubinsky, 42
Connected to:
Albert Rubinshteyn, 57Alex Rubinski, 35Christine Rubinski, 75Arielle Rubinson, 38David L Rubinson, 55Laura H Rubinson, 40Seth I Rubinson, 52Thomas Rubinson, 60Alina A Rubinstein, 79

Boris Rubinsky Phones & Addresses

  • 937 Contra Costa Dr, El Cerrito, CA 94530
  • 1619 Sonoma Ave, Berkeley, CA 94707 (510) 525-3764 (510) 527-9819
  • Albany, CA
  • Emeryville, CA
  • Alameda, CA
  • 1619 Sonoma Ave, Berkeley, CA 94707 (510) 710-2934

Work

Company: Hebrew university Position: Professor

Emails

b***[email protected]

Industries

Research

Resumes

Resumes

Boris Rubinsky Photo 1

Professor

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Location:
937 Contra Costa Dr, El Cerrito, CA 94530
Industry:
Research
Work:
Hebrew University
Professor

Business Records

Name / Title
Company / Classification
Phones & Addresses
Boris Rubinsky
Ldys, LLC
Biomedical Consulting and Investment · Investment & Business Development · Business Services at Non-Commercial Site · Nonclassifiable Establishments
930 Montgomery St, San Francisco, CA 94133
937 Contra Costa Dr, Richmond, CA 94530
353 3 Ave, San Francisco, CA 94118

Publications

Us Patents

Electrical Impedance Tomography To Control Electroporation

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US Patent:
6387671, May 14, 2002
Filed:
Jul 19, 2000
Appl. No.:
09/619021
Inventors:
Boris Rubinsky - Albany CA
Yong Huang - Albany CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12N 1300
US Classification:
4351737, 4351731, 4352871, 4352887
Abstract:
Images created by electrical impedance tomography (EIT) are used to adjust one or more electrical parameters and obtain a desired degree of electroporation of cells in tissue. The parameters include current, voltage and a combination thereof. The cells are subjected to conditions such that they become permeabilized but are preferably not subjected to conditions which result in irreversible pore formation and cell death. The electroporation can analyze cell membranes, diagnose tissues and the patient as well as to move materials into and out of cells in a controlled manner.

Controlled Electroporation And Mass Transfer Across Cell Membranes

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US Patent:
6403348, Jun 11, 2002
Filed:
Jul 19, 2000
Appl. No.:
09/618949
Inventors:
Boris Rubinsky - Albany CA
Yong Huang - Albany CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12M 1300
US Classification:
4351737, 4351731, 4352871, 4352887
Abstract:
Electroporation is performed in a controlled manner in either individual or multiple biological cells or biological tissue by monitoring the electrical impedance, defined herein as the ratio of current to voltage in the electroporation cell. The impedance detects the onset of electroporation in the biological cell(s), and this information is used to control the intensity and duration of the voltage to assure that electroporation has occurred without destroying the cell(s). This is applicable to electroporation in general. In addition, a particular method and apparatus are disclosed in which electroporation and/or mass transfer across a cell membrane are accomplished by securing a cell across an opening in a barrier between two chambers such that the cell closes the opening. The barrier is either electrically insulating, impermeable to the solute, or both, depending on whether pore formation, diffusive transport of the solute across the membrane, or both are sought. Electroporation is achieved by applying a voltage between the two chambers, and diffusive transport is achieved either by a difference in solute concentration between the liquids surrounding the cell and the cell interior or by a differential in concentration between the two chambers themselves.

Cell/Tissue Analysis Via Controlled Electroporation

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US Patent:
6482619, Nov 19, 2002
Filed:
Jul 19, 2000
Appl. No.:
09/618951
Inventors:
Boris Rubinsky - Albany CA
Yong Huang - Albany CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12N 1300
US Classification:
4351737, 4351731, 4352871, 4352887
Abstract:
An electrical current is created across an electrically conductive medium comprising a cell which may be part of a tissue of a living organism. A first electrical parameter which may be current, voltage, or electrical impedance is measured. A second electrical parameter which may be current, voltage or a combination of both is then adjusted and/or analyzed. Adjustments are carried out to facilitate analysis and/or obtain a desired degree of electroporation. Analysis is carried out to determine characteristics of the cell membrane and/or tissue.

Controlled Electroporation And Mass Transfer Across Cell Membranes

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US Patent:
6562604, May 13, 2003
Filed:
May 22, 2001
Appl. No.:
09/863117
Inventors:
Boris Rubinsky - Albany CA
Yong Huang - Berkeley CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12N 1300
US Classification:
4351736
Abstract:
Electroporation is performed in a controlled manner in either individual or multiple biological cells or biological tissue by monitoring the electrical impedance, defined herein as the ratio of current to voltage in the electroporation cell. The impedance detects the onset of electroporation in the biological cell(s), and this information is used to control the intensity and duration of the voltage to assure that electroporation has occurred without destroying the cell(s). This is applicable to electroporation in general. In addition, a particular method and apparatus are disclosed in which electroporation and/or mass transfer across a cell membrane are accomplished by securing a cell across an opening in a barrier between two chambers such that the cell closes the opening. The barrier is either electrically insulating, impermeable to the solute, or both, depending on whether pore formation, diffusive transport of the solute across the membrane, or both are sought. Electroporation is achieved by applying a voltage between the two chambers, and diffusive transport is achieved either by a difference in solute concentration between the liquids surrounding the cell and the cell interior or by a differential in concentration between the two chambers themselves.

Device And Method For Classification Of Tissue

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US Patent:
6594518, Jul 15, 2003
Filed:
Jan 23, 1998
Appl. No.:
09/012602
Inventors:
David A. Benaron - Portola Valley CA, 94028
Boris Rubinsky - Albany CA, 94707
International Classification:
A61B 500
US Classification:
600477, 600342, 600475, 600478, 600567
Abstract:
A diagnostic monitor for classifying biological tissue in which a light emitter ( ) is optically coupled to the tissue to be diagnosed ( ) and a light detector ( ) is optically coupled to the tissue to detect a portion of the light which passes through the tissue. The tissue classifier ( ) receives a signal from the detector and provides an optical classification output signal ( ), wherein the tissue is classified by type or state, either for detection, localization, or imaging. A method of classifying tissue is also described.

Method And Apparatus For Remote Imaging Of Biological Tissue By Electrical Impedance Tomography Through A Communications Network

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US Patent:
6725087, Apr 20, 2004
Filed:
Sep 19, 2000
Appl. No.:
09/664026
Inventors:
Boris Rubinsky - Albany CA
David Otten - Berkeley CA
Assignee:
Telectroscan, Inc. - Berkeley CA
International Classification:
A61B 505
US Classification:
600547, 128920, 705 3
Abstract:
A method and apparatus for imaging the internal structure of biological tissue from a remote location using electrical impedance tomography. The method and apparatus accomplish this by separating the functions of data acquisition from those of processing and imaging, and by connecting the data acquisition, processing and imaging components through a communications network, thus permitting the data acquisition, processing and imaging functions to be carried out at disparate locations within said network.

Cell Viability Detection Using Electrical Measurements

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US Patent:
6927049, Aug 9, 2005
Filed:
Feb 19, 2002
Appl. No.:
10/079940
Inventors:
Boris Rubinsky - Albany CA, US
Yong Huang - Albany CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12N013/00
US Classification:
4351737
Abstract:
A method of determining information about cell viability and other characteristics relating to cell membrane permeability is disclosed. The method involves determining the effect of a cell on current flow and relating that effect to a known standard which standard may be a known healthy cell and thereby deducing the viability of the cell being tested. The cells being tested can be subjected to different environmental conditions such as surrounding chemicals, temperature, pH and pressure to determine the effects of such conditions on cell viability and/or cell permeability. The cell being tested can be in a cell suspension, grown on s ubstarte, in tissue in vitro or in tissue in vivo. The method provides substantially instantaneous results and need not include the use of dyes or other markers.

Controlled Electroporation And Mass Transfer Across Cell Membranes In Tissue

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US Patent:
7053063, May 30, 2006
Filed:
May 26, 2005
Appl. No.:
11/139012
Inventors:
Boris Rubinsky - Milpitas CA, US
Yong Huang - Milpitas CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 31/713
US Classification:
514 44, 435461, 4352852
Abstract:
Electroporation is performed in a controlled manner in individual and multiple biological cells present in biological tissue by monitoring the electrical impedance, defined herein as the ratio of current to voltage in the electroporation cell. The impedance detects the onset of electroporation in the biological cell(s), and this information is used to control the intensity and duration of the voltage to assure that electroporation has occurred without destroying the cell(s). This is applicable to electroporation in general.
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Boris Living Rubinsky from El Cerrito, CA, age ~76 Get Report