Resumes
Resumes
Beverley Wynne Phones & Addresses
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1138 Strathaven Dr N #6B, Columbus, OH 43085 (614) 846-1204
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Worthington, OH
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Winter Park, CO
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5445 N Sheridan Rd, Chicago, IL 60640
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7588 Cutters Edge Ct, Dublin, OH 43016 (614) 846-1204
Work
Position:
Administration/Managerial
Education
Degree:
Graduate or professional degree
Publications
Us Patents
Composition For Inhalation Comprising Delta-9-Tetrahydrocannabinol In A Semiaqueous Solvent
View pageUS Patent:
20040162336, Aug 19, 2004
Filed:
Sep 5, 2003
Appl. No.:
10/656304
Inventors:
Andrea McPhillips - Dublin OH, US
Julia Economou - Dublin OH, US
Mahendra Dedhiya - Doublin OH, US
Beverley Wynne - Worthington OH, US
Julia Economou - Dublin OH, US
Mahendra Dedhiya - Doublin OH, US
Beverley Wynne - Worthington OH, US
International Classification:
A61K031/353
US Classification:
514/454000
Abstract:
A stable composition for rapid delivery by inhalation to the lungs, and subsequently to the bloodstream, is provided. The composition comprises a therapeutically effective amount of delta-9-tetrahydrocannabinol in a pharmaceutically-acceptable semiaqueous solvent comprising an alcohol, water and a glycol. A composition comprising volumetric ratios of ethanol:water:propylene glycol selected from those in the range of from 10-70:10-30:20-80, respectively, having a combined total of 100 is also provided. A sterile and/or preserved sealed unit-or multi-unit dosage form of delta-9-tetrahydrocannabinol is further provided.
Stable Composition For Inhalation Therapy Comprising Delta-9-Tetrahydrocannabinol And Semiaqueous Solvent Therefor
View pageUS Patent:
6747058, Jun 8, 2004
Filed:
Aug 15, 2000
Appl. No.:
09/639289
Inventors:
Mahendra G. Dedhiya - Dublin OH
Julia J. Economou - HIlliard OH
Andrea M. McPhillips - Columbus OH
Beverley A. Wynne - Worthington OH
Julia J. Economou - HIlliard OH
Andrea M. McPhillips - Columbus OH
Beverley A. Wynne - Worthington OH
Assignee:
Unimed Pharmaceuticals, Inc.
International Classification:
A01N 4316
US Classification:
514454, 424 43
Abstract:
A formulation of delta-9-tetrahydrocannabinol in a semi-aqueous solvent, such as 35:10:55 alcohol:water:propylene glycol (v/v), produces a stable clear solution near the solubility point of the drug. Because delta-9-tetrahydrocannabinol has poor affinity for the formulation, it is able to partition out and transport across cell membranes to reach the bloodstream quickly. This has been demonstrated by the comparative t values achieved in single dose intravenous and 14 day multiple dose inhalation studies conducted in dogs and rats.