US Patent:
20110091510, Apr 21, 2011
Inventors:
Tanmay P. Lele - Gainesville FL, US
Fan Ren - Gainesville FL, US
Benjamin George Keselowsky - Gainesville FL, US
Jiyeon Lee - Gainesville FL, US
Anand Gupte - Gainesville FL, US
Byung-Hwan Chu - Gainesville FL, US
Karl Zawoy - High Springs FL, US
International Classification:
A61K 9/00
A61K 31/727
A61K 38/02
A61K 33/24
A61K 31/407
C12N 5/071
A61P 43/00
B32B 9/00
C01G 9/02
C01G 23/047
C01B 33/02
C01B 21/06
A61L 33/00
B82Y 5/00
B82Y 40/00
US Classification:
424400, 514 56, 514 11, 424649, 514410, 435375, 428389, 428401, 428379, 428392, 4282921, 4282924, 4282974, 423622, 423610, 423348, 423409, 427 224, 977762, 977811, 977778, 977783, 977882, 977906
Abstract:
The subject invention concerns nanorods, compositions and substrates comprising nanorods, and methods of making and using nanorods and nanorod compositions and substrates. In one embodiment, the nanorod is composed of Zinc oxide (ZnO). In a further embodiment, a nanorod of the invention further comprises SiOor TiO. In a specific embodiment, a nanorod of the invention is composed of ZnO coated with SiO. Nanorods of the present invention are useful as an adhesion-resistant biomaterial capable of reducing viability in anchorage-dependent cells.