US Patent:
20060205649, Sep 14, 2006
Inventors:
Avtar Roopra - Madison WI, US
Thomas Sutula - Madison WI, US
Barry Schoenike - Belleville WI, US
International Classification:
A61K 38/17
A61K 31/35
A61K 31/70
A61K 31/19
US Classification:
514012000, 514023000, 514460000, 514557000
Abstract:
This invention provides methods for modulating cellular gene expression for genes operably linked to an NRSE element that is recognized by an NRSF transcriptional repressor, by changing the concentration of reduced nicotinamide adenine dinucleotide (NADH) in the cell.