Ayan Ghoshal Phones & Addresses
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198 Algonquin Trl, Ashland, MA 01721 (508) 881-1308
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Somerville, MA
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Nashville, TN
Publications
Us Patents
Neuronal Assay Method Involving Calcineurin
View pageUS Patent:
20200256880, Aug 13, 2020
Filed:
Aug 16, 2018
Appl. No.:
16/639251
Inventors:
- Cambridge MA, US
Yan-Ling Zhang - Lexington MA, US
Ayan Ghoshal - Somerville MA, US
Jeffrey Cottrell - Sterling MA, US
Yan-Ling Zhang - Lexington MA, US
Ayan Ghoshal - Somerville MA, US
Jeffrey Cottrell - Sterling MA, US
International Classification:
G01N 33/68
G01N 33/52
C07K 16/18
G01N 33/52
C07K 16/18
Abstract:
This disclosure relates to methods of detecting and quantifying neuronal activation. This disclosure further relates to a particular phosphorylation of calcineurin A alpha (CNAα) at serine 469 (S469) of the amino acid sequence of the protein as a marker for neuronal activation, antibodies recognizing that phosphorylated form of CNAα, and uses of such antibodies, for example, in various neuronal activity assays and related kits.