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Athma A Pai

from Newton, MA
Age ~39
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Also known as:
Vasanti Pai, Pai Ven
Related to:
Vasanti V Pai, 83Venkatrao K Pai, 86
Connected to:
Abhijeet M Pai, 42Aditya B Pai, 32Ashwini B Pai, 39Bharat N Pai, 59Bina A Pai, 63Caroline A Pai, 63Dave A Pai, 43Deepali K Pai, 45Diana X Pai, 53Doris J Pai, 49

Athma Pai Phones & Addresses

  • Newton, MA
  • 24A Maple Ave APT 2, Cambridge, MA 02139
  • 5345 Harper Ave, Chicago, IL 60615
  • Stamford, CT

Publications

Us Patents

Anti-Slc6A1 Oligonucleotides And Related Methods

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US Patent:
20230041016, Feb 9, 2023
Filed:
Dec 4, 2020
Appl. No.:
17/781554
Inventors:
Athma A. PAI - Cambridge MA, US
Jonathan K. WATTS - Worcester MA, US
Kaitlyn VALLA - Worcester MA, US
Eraj Shafiq KHOKHAR - Worcester MA, US
International Classification:
C12N 15/113
Abstract:
The present disclosure provides antisense oligonucleotides that bind to a splice modulatory element target region in an SLC6A1 RNA transcript. The present disclosure provides antisense oligonucleotides that increase the expression of a functional protein encoded by the SLC6A1 RNA transcript in a cell (i.e., GABA Transporter 1, GAT-1). The present disclosure also provides methods of treating a disease or disorder associated with non-productive SLC6A1 RNA transcripts.

Identifying Non-Productive Splice Sites

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US Patent:
20230022489, Jan 26, 2023
Filed:
Dec 4, 2020
Appl. No.:
17/781569
Inventors:
Athma A. PAI - Cambridge MA, US
Jonathan K. WATTS - Worcester MA, US
Kaitlyn VALLA - Worcester MA, US
Eraj Shafiq KHOKHAR - Worcester MA, US
Zachary KARTJE - Worcester MA, US
International Classification:
C12N 15/113
C12Q 1/6834
A61P 43/00
Abstract:
The present disclosure provides methods of identifying non-productive splice sites in target RNA transcripts and antisense oligonucleotides that increase the expression of said target RNA transcripts. In an embodiment, the target RNA transcript comprises ADAR, ARSA, ATPIA2, CACNAIA, DNMI, EIF2BI, EIF2B2, EIF2B5, IDUA, MFSD8, NF2, NPC1L PEXI, PRICKLE2, PRRT2, RAM, SETD5, SHANKS, SLC6A1, STXBPI, STX1B, and TCF4.
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Athma A Pai from Newton, MA, age ~39 Get Report