Inventors:
Arvind Krishna Bhide - Newark DE
Carol L. Bush - Rising Sun MD
Theodore William Frentzel - Newark DE
Mary Kolean Koeppe - Landenberg PA
Louis G. Rosanio - Wilmington DE
Assignee:
E. I. du Pont de Nemours and Company - Wilmington DE
International Classification:
C12M 132
Abstract:
Methods and apparati for screening compounds for agricultural activity has now been developed which employ e. g. , intact plants grown in microtiter plates on very small amounts of plant growth media containing a test compound. In comparison to the standard greenhouse screen, the microscreen requires vastly less space, labor, and test compound. However, unlike in vitro screens, responses of intact plants are assayed. Using the microscreen, high-throughput screening of test compounds can be accomplished using whole plant responses as the assay.