US Patent:
20110319436, Dec 29, 2011
Inventors:
Peter Walter - San Francisco CA, US
Alexei Korennykh - San Francisco CA, US
Kevan M. Shokat - San Francisco CA, US
Chao Zhang - Santa Cruz CA, US
Robert Stroud - San Francisco CA, US
Pascal Egea - San Francisco CA, US
Andrei Korostelev - Santa Cruz CA, US
Arvin Dar - San Francisco CA, US
Sebastian Bernales - Santiago, CL
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 31/517
C07D 403/12
C07D 409/14
C07D 417/14
A61K 31/506
C12N 5/071
A61K 31/404
A61P 35/00
A61P 29/00
A61P 25/00
A61P 3/10
A61P 27/02
A61P 25/28
A61P 25/16
C12Q 1/48
C07D 403/14
US Classification:
51426623, 544324, 544284, 514275, 435375, 514414, 436 86, 435 61
Abstract:
Disclosed herein are, inter alia, compositions for modulating Ire1, Src, or Abl, methods for identifying modulating activity in test compounds, and methods for treating diseases caused by the activity or inactivity of Ire1, Src, or Abl.