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Arthur J Chirino

from Camarillo, CA
Age ~61
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Also known as:
Arthur Dr Chirino, Arthur Jorge Chirino, Authur J Chirino, Arthur J Lichtman, Arthur G Chirimo
Phone and address:
6816 Pueblo Vis, Camarillo, CA 93012
(805) 482-4799
Related to:
Melissa Marquez, 46Elizabeth A Ziegler, 48Anthony B Roslund, 50David Coons, 64Val Ziegler, 71Candace Ziegler, 45
Connected to:
Alberto L Chirino, 87Alex Chirino, 58Arturo A Chirinos, 38Barbara M Chirinos, 64Edward Chirinos, 39Edwin A Chirinos, 43Elia Chirinos, 51Felix Chirinos, 55Gabriel Chirinos, 55Gladys Chirinos, 79

Arthur Chirino Phones & Addresses

  • 6816 Pueblo Vis, Camarillo, CA 93012 (805) 482-4799
  • Studio City, CA
  • Glendale, CA
  • Wayne, PA
  • West Hollywood, CA
  • Hamden, CT
  • Ventura, CA
  • 11538 Duque Dr, Studio City, CA 91604

Work

Company: Xencor Dec 2019 Position: Senior director, product control strategy and manufacturing

Education

Degree: Doctorates, Doctor of Philosophy School / High School: University of California, Los Angeles 1986 to 1993 Specialities: Biochemistry

Skills

Biochemistry • Molecular Biology • Drug Discovery • Antibody Engineering • Immunogenicity • Cmc • Product Quality • Assay Development • Antibodies • Protein Chemistry • Quality Assurance • Elisa • Hplc • Life Sciences • Structural Biology • Biotechnology • Clinical Research • Pharmaceutical Industry • Technology Transfer • Biopharmaceuticals • Drug Development • Regulatory Submissions • Gmp • Ich Compliance • U.s. Food and Drug Administration • Standard Operating Procedure • Commercialization • Quality System • Monoclonal Antibodies • Good Laboratory Practice • Oncology • Immunology • Regulatory Affairs • Change Management • Change Control • Business Process Improvement • Cross Functional Team Leadership • Root Cause Analysis • Corrective and Preventive Action • Regulatory Requirements • Formulation • Protein Purification

Languages

English • Spanish • Portuguese

Industries

Biotechnology

Resumes

Resumes

Arthur Chirino Photo 1

Senior Director, Product Control Strategy And Manufacturing

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Location:
6816 Pueblo Vis, Camarillo, CA 93012
Industry:
Biotechnology
Work:
Xencor
Senior Director, Product Control Strategy and Manufacturing
Amgen May 2010 - Jan 2014
Product Quality Director
Amgen May 2010 - Jan 2014
Principal Product Quality Leader
Amgen Aug 2006 - May 2010
Director, Quality Assurance
Centocor May 2005 - Aug 2006
Assistant Director
Education:
University of California, Los Angeles 1986 - 1993
Doctorates, Doctor of Philosophy, Biochemistry University of California, Los Angeles 1981 - 1986
Bachelors, Bachelor of Arts, Bachelor of Science, Biochemistry, Physics
Skills:
Biochemistry
Molecular Biology
Drug Discovery
Antibody Engineering
Immunogenicity
Cmc
Product Quality
Assay Development
Antibodies
Protein Chemistry
Quality Assurance
Elisa
Hplc
Life Sciences
Structural Biology
Biotechnology
Clinical Research
Pharmaceutical Industry
Technology Transfer
Biopharmaceuticals
Drug Development
Regulatory Submissions
Gmp
Ich Compliance
U.s. Food and Drug Administration
Standard Operating Procedure
Commercialization
Quality System
Monoclonal Antibodies
Good Laboratory Practice
Oncology
Immunology
Regulatory Affairs
Change Management
Change Control
Business Process Improvement
Cross Functional Team Leadership
Root Cause Analysis
Corrective and Preventive Action
Regulatory Requirements
Formulation
Protein Purification
Languages:
English
Spanish
Portuguese

Publications

Us Patents

Optimized Fc Variants

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US Patent:
7317091, Jan 8, 2008
Filed:
Mar 26, 2004
Appl. No.:
10/822231
Inventors:
Gregory Alan Lazar - Glendale CA, US
Arthur J. Chirino - Camarillo CA, US
Wei Dang - Pasadena CA, US
John R. Desjarlais - Pasadena CA, US
Stephen Kohl Doberstein - San Francisco CA, US
Robert J. Hayes - Radnor PA, US
Sher Bahadur Karki - Pasadena CA, US
Omid Vafa - Monrovia CA, US
Assignee:
Xencor, Inc. - Monrovia CA
International Classification:
C07K 16/00
C12P 21/08
US Classification:
5303871, 5303873
Abstract:
The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.

Globular Adiponectin Variants

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US Patent:
7592423, Sep 22, 2009
Filed:
May 30, 2006
Appl. No.:
11/421055
Inventors:
Jonathan Zalevsky - Riverside CA, US
Duc-Hanh Thi Nguyen - Sylmar CA, US
Gregory L. Moore - Monrovia CA, US
Sergei A. Ezhevsky - San Diego CA, US
John R. Desjarlais - Pasadena CA, US
Arthur J. Chirino - Camarillo CA, US
Darian Cash - Los Angeles CA, US
Matthew J. Bernett - Monrovia CA, US
Assignee:
Xencor, Inc. - Monrovia CA
International Classification:
C07K 14/00
C07K 1/00
C07K 17/00
C07K 16/00
A61K 38/24
A61K 38/27
US Classification:
530350, 530395, 530397, 530399
Abstract:
An adiponectin variant with one or more amino acid modifications relative to a corresponding parent adiponectin, wherein the adiponectin variant is not glycosylated, the adiponectin variant does not have residues 1-100 relative to human adiponectin, and wherein the solubility of the variant is improved by at least 3-fold relative to residues 110-244 of human adiponectin.

Optimized Fc Variants And Methods For Their Generation

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US Patent:
7662925, Feb 16, 2010
Filed:
Jul 7, 2006
Appl. No.:
11/483250
Inventors:
Gregory Alan Lazar - Glendale CA, US
Arthur J. Chirino - Camarillo CA, US
Wei Dang - Pasadena CA, US
John R. Desjarlais - Pasadena CA, US
Stephen Kohl Doberstein - San Francisco CA, US
Robert J. Hayes - Radnor PA, US
Sher Bahadur Karki - Pasadena CA, US
Omid Vafa - Monrovia CA, US
Assignee:
Xencor, Inc. - Monrovia CA
International Classification:
C07K 16/00
C12P 21/08
C07K 1/00
US Classification:
5303871, 5303873
Abstract:
The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.

Pharmaceutical Compositions Of Adiponectin Variants And Methods Of Storage

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US Patent:
7678886, Mar 16, 2010
Filed:
May 30, 2006
Appl. No.:
11/421061
Inventors:
Jonathan Zalevsky - Riverside CA, US
Duc-Hanh Thi Nguyen - Sylmar CA, US
Gregory L. Moore - Monrovia CA, US
Sergei A. Ezhevsky - San Diego CA, US
John R. Desjarlais - Pasadena CA, US
Arthur J. Chirino - Camarillo CA, US
Darian Cash - Los Angeles CA, US
Matthew J. Bernett - Monrovia CA, US
Assignee:
Xencor, Inc. - Monrovia CA
International Classification:
C07K 14/00
C07K 1/00
C07K 17/00
C07K 16/00
A61K 38/24
A61K 38/27
US Classification:
530350, 530395, 530397, 530399
Abstract:
A composition comprising an adiponectin variant at a concentration of at least 2. 0 mg/mL, and a pharmaceutically acceptable carrier, wherein less than 20% of said adiponectin variant would aggregate after storage at 4 C. for one week in 10 mM PO, 150 mM NaCl buffer.

Adiponectin Variants

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US Patent:
7709607, May 4, 2010
Filed:
May 30, 2006
Appl. No.:
11/421059
Inventors:
Jonathan Zalevsky - Riverside CA, US
Duc-Hanh Thi Nguyen - Sylmar CA, US
Gregory L. Moore - Monrovia CA, US
Sergei A. Ezhevsky - San Diego CA, US
John R. Desjarlais - Pasadena CA, US
Arthur J. Chirino - Camarillo CA, US
Darian Cash - Los Angeles CA, US
Matthew J. Bernett - Monrovia CA, US
Assignee:
Xencor, Inc. - Monrovia CA
International Classification:
C07K 1/00
C07K 14/00
C07K 16/00
C07K 17/00
A61K 38/24
A61K 38/27
US Classification:
530350, 530395, 530397, 530399
Abstract:
An adiponectin variant with one or more amino acid modifications relative to a corresponding parent adiponectin, wherein the solubility of the variant is improved by at least 3-fold relative to residues 110-244 of human adiponectin.

Method Of Treatment Using Adiponectin Variants

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US Patent:
7749956, Jul 6, 2010
Filed:
May 30, 2006
Appl. No.:
11/421060
Inventors:
Jonathan Zalevsky - Riverside CA, US
Duc-Hanh Thi Nguyen - Sylmar CA, US
Gregory L. Moore - Monrovia CA, US
Sergei A. Ezhevsky - San Diego CA, US
John R. Desjarlais - Pasadena CA, US
Arthur J. Chirino - Camarillo CA, US
Darian Cash - Los Angeles CA, US
Matthew J. Bernett - Monrovia CA, US
Assignee:
Xencor, Inc. - Monrovia CA
International Classification:
A01N 37/18
A61K 38/16
A61K 38/00
US Classification:
514 2, 514 8, 514 21
Abstract:
A method of treating a mammal with an adiponectin mediated disorder comprising administering a therapeutically effective amount of an adiponectin variant with at least a 3-fold increased solubility relative to residues 110-244 of human adiponectin.

Optimized Fc Variants And Methods For Their Generation

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US Patent:
8039592, Oct 18, 2011
Filed:
Oct 31, 2007
Appl. No.:
11/981823
Inventors:
Gregory Alan Lazar - Alhambra CA, US
Arthur J. Chirino - Camarillo CA, US
Wei Dang - Pasadena CA, US
John R. Desjarlais - Pasadena CA, US
Stephen K. Doberstein - San Francisco CA, US
Robert J. Hayes - Radnor PA, US
Sher Bahadur Karki - Pasadena CA, US
Omid Vafa - Monrovia CA, US
Assignee:
Xencor, Inc. - Monrovia CA
International Classification:
C07K 17/00
C07K 16/00
C12P 21/08
A61K 39/395
US Classification:
5303871, 530350, 5303873, 5303881, 53038815
Abstract:
The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.

Optimized Fc Variants And Methods For Their Generation

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US Patent:
8093357, Jan 10, 2012
Filed:
Jul 7, 2006
Appl. No.:
11/483378
Inventors:
Gregory Alan Lazar - Alhambra CA, US
Arthur J. Chirino - Camarillo CA, US
Wei Dang - Pasadena CA, US
John R. Desjarlais - Pasadena CA, US
Stephen Kohl Doberstein - San Francisco CA, US
Robert J. Hayes - Radnor PA, US
Sher Bahadur Karki - Pasadena CA, US
Omid Vafa - Monrovia CA, US
Assignee:
Xencor, Inc. - Monrovia CA
International Classification:
C07K 1/00
C07K 16/00
C07K 17/00
US Classification:
5303871, 5303873, 5303881, 530350
Abstract:
The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
Control profile
Arthur J Chirino from Camarillo, CA, age ~61 Get Report