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Aregahegn Yifru Phones & Addresses

  • 478 Mccall Dr, Benicia, CA 94510
  • Pleasant Hill, CA
  • Arlington, MA
  • Somerville, MA
  • Boston, MA
  • Minneapolis, MN

Work

Company: Novartis Sep 2007 Position: Scientist

Education

School / High School: AAU

Skills

Drug Discovery • Medicinal Chemistry • Drug Design • Drug Development • Lead Change • Lc Ms • Pharmaceutical Industry • Hplc • Biotechnology • Pharmacology • Organic Chemistry • Organic Synthesis • Purification • Pharmacokinetics • Lifesciences • Biochemistry • Chemistry • Adme • Dmpk • Drug Metabolism

Industries

Pharmaceuticals

Resumes

Resumes

Aregahegn Yifru Photo 1

Scientist Ii

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Location:
478 Mccall Dr, Benicia, CA 94510
Industry:
Pharmaceuticals
Work:
Novartis since Sep 2007
Scientist

Novartis Institute for BioMedical Research since 2004
Scientist
Education:
AAU
Skills:
Drug Discovery
Medicinal Chemistry
Drug Design
Drug Development
Lead Change
Lc Ms
Pharmaceutical Industry
Hplc
Biotechnology
Pharmacology
Organic Chemistry
Organic Synthesis
Purification
Pharmacokinetics
Lifesciences
Biochemistry
Chemistry
Adme
Dmpk
Drug Metabolism

Publications

Us Patents

Drug Conjugates Of Ion Channel Modulating Compounds

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US Patent:
7786119, Aug 31, 2010
Filed:
Mar 31, 2005
Appl. No.:
11/547419
Inventors:
Elizabeth L. S. Cheu - Halifax, CA
Lewis Siu Leung Choi - Burnaby, CA
Doug Ta Hung Chou - Vancouver, CA
Allen W. Davidoff - Calgary, CA
Alan M. Ezrin - Miami FL, US
Grace Jung - New Westminster, CA
Bertrand M. C. Plouvier - Vancouver, CA
Aregahegn S. Yifru - Somerville MA, US
Assignee:
Cardiome Pharma Corp. - Vancouver
International Classification:
A61K 31/501
US Classification:
51425203, 51425401, 5142621, 514369, 514406, 514422, 514424, 548541, 548544, 5483641, 548182, 548187, 544238, 544372, 540521
Abstract:
This invention is directed to drug conjugates of certain ion channel modulating compounds having the following formula:.

Organic Compounds And Their Uses

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US Patent:
7825152, Nov 2, 2010
Filed:
Apr 9, 2007
Appl. No.:
11/697894
Inventors:
Trixi Brandl - Basel, CH
Jiping Fu - Arlington MA, US
Francois Lenoir - Waltham MA, US
David Thomas Parker - Lexington MA, US
Michael Patane - Reading MA, US
Branko Radetich - Boston MA, US
Prakash Raman - Acton MA, US
Pascal Rigollier - Mulhouse, FR
Mohindra Seepersaud - Belmont MA, US
Oliver Simic - Basel, CH
Aregahegn Yifru - Somerville MA, US
Rui Zheng - Arlington MA, US
Assignee:
Novartis AG - Basel
International Classification:
C07D 417/12
C07D 403/12
C07D 401/12
C07D 409/12
C07D 417/14
C07D 405/12
C07D 413/12
C07D 405/04
C07D 403/04
C07D 413/14
C07D 409/14
C07D 405/14
C07D 207/00
C07D 209/96
A61K 31/5377
A61K 31/506
A61K 31/497
A61K 31/4439
A61K 31/454
A61K 31/427
A61K 31/422
A61K 31/4178
A61K 31/4155
A61K 31/403
US Classification:
514409, 51425505, 514278, 514372, 514374, 5142372, 514256, 514397, 514406, 514381, 514275, 548408, 548214, 548216, 5483007, 5483575, 548253, 544230, 544 70, 546 15
Abstract:
The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.

Organic Compounds And Their Uses

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US Patent:
8008263, Aug 30, 2011
Filed:
Oct 10, 2008
Appl. No.:
12/249186
Inventors:
Shawn D. Britt - Andover MA, US
Lech Andrzej Ciszewski - Morristown NJ, US
Jiping Fu - Arlington MA, US
Subramanian Karur - Arlington MA, US
Yugang Liu - Bridgewater NJ, US
Peichao Lu - Malden MA, US
David Thomas Parker - Lexington MA, US
Mahavir Prashad - Montville NJ, US
Prakash Raman - Acton MA, US
Pascal Rigollier - Mulhouse, FR
Mohindra Seepersaud - Acton MA, US
Aregahegn Yifru - Somerville MA, US
Rui Zheng - Waltham MA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 38/07
A61K 38/55
US Classification:
514 219, 514 37, 514 201, 514 203, 530330
Abstract:
The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.

Deuterated Aminocyclohexyl Ether Compounds And Processes For Preparing Same

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US Patent:
8022098, Sep 20, 2011
Filed:
Feb 26, 2010
Appl. No.:
12/713605
Inventors:
Doug Ta Hung Chou - Vancouver, CA
Bertrand M. C. Plouvier - Vancouver, CA
Peter Pang - Richmond, CA
James Gee Ken Yee - Vancouver, CA
Jeffery Jerome Wheeler - Surrey, CA
Aregahegn S. Yifru - Somerville MA, US
Allen W. Davidoff - Calgary, CA
Assignee:
Cardiome Pharma Corp. - Vancouver, BC
International Classification:
A61K 31/40
C07D 207/00
US Classification:
514424, 548541
Abstract:
This invention is directed to deuterated aminocyclohexyl ether compounds and processes for preparing same and methods of using same.

Organic Compounds And Their Uses

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US Patent:
8211932, Jul 3, 2012
Filed:
Sep 10, 2010
Appl. No.:
12/879644
Inventors:
Michael Patane - Andover MA, US
Prakash Raman - Acton MA, US
David Thomas Parker - Lexington MA, US
Jiping Fu - Arlington MA, US
Branko Radetich - Boston MA, US
Mohindra Seepersaud - Belmont MA, US
Aregahegn Yifru - Somerville MA, US
Rui Zheng - Arlington MA, US
Trixi Brandl - Basel, CH
Francois Lenoir - Waltham MA, US
Pascal Rigollier - Mulhouse, FR
Oliver Simic - Basel, CH
Assignee:
Novartis AG - Basel
International Classification:
C07D 417/12
C07D 403/12
C07D 401/12
C07D 409/12
C07D 417/14
C07D 405/12
C07D 413/12
C07D 405/04
C07D 403/04
C07D 413/14
C07D 409/14
C07D 405/14
C07D 207/00
C07D 209/96
A61K 31/5377
A61K 31/506
A61K 31/497
A61K 31/4439
A61K 31/454
A61K 31/427
A61K 31/422
A61K 31/4178
A61K 31/4155
A61K 31/403
US Classification:
514409, 51425505, 514278, 514372, 514374, 5142372, 514256, 514397, 514406, 514381, 514275, 548408, 548214, 548216, 5483007, 5483575, 548253, 544230, 544 70, 546 15
Abstract:
The present application describes organic compounds of the Formula I that are useful for the treatment, prevention and/or amelioration of human diseases.

Organic Compounds And Their Uses

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US Patent:
8222425, Jul 17, 2012
Filed:
Jul 19, 2011
Appl. No.:
13/185683
Inventors:
Shawn D. Britt - Cambridge MA, US
Lech Andrzej Ciszewski - East Hanover NJ, US
Jiping Fu - Cambridge MA, US
Subramanian Karur - Cambridge MA, US
Yugang Liu - East Hanover NJ, US
Peichao Lu - Cambridge MA, US
David Thomas Parker - Cambridge MA, US
Mahavir Prashad - East Hanover NJ, US
Prakash Raman - Cambridge MA, US
Pascal Rigollier - Basel, CH
Mohindra Seepersaud - Cambridge MA, US
Aregahegn Yifru - Cambridge MA, US
Rui Zheng - Cambridge MA, US
Assignee:
Novartis AG - Basel
International Classification:
C07D 207/00
US Classification:
548427, 548215, 548217, 548225, 548400, 548416, 548420, 548426, 548428, 548448, 514 11, 514359, 514374, 514408, 514410, 514411, 514419
Abstract:
The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.

Organic Compounds And Their Uses

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US Patent:
8445527, May 21, 2013
Filed:
May 22, 2012
Appl. No.:
13/477866
Inventors:
Michael Patane - Andover MA, US
Prakash Raman - Acton MA, US
David Thomas Parker - Lexington MA, US
Jiping Fu - Arlington MA, US
Branko Radetich - Boston MA, US
Mohindra Seepersaud - Belmont MA, US
Aregahegn Yifru - Somerville MA, US
Rui Zheng - Arlington MA, US
Trixi Brandl - Basel, CH
Francois Lenoir - Waltham MA, US
Pascal Rigollier - Mulhouse, FR
Oliver Simic - Basel, CH
Assignee:
Novartis AG - Basel
International Classification:
A61K 31/5377
A61K 31/506
A61K 31/497
A61K 31/4439
A61K 31/454
A61K 31/427
A61K 31/422
A61K 31/4178
A61K 31/4155
A61K 31/403
US Classification:
514409, 51425505, 514278, 514372, 514374, 5142372, 514256, 514397, 514406, 514381, 514275
Abstract:
The present invention provides a method of treating a HCV infection in a subject in need thereof by administering a compound of Formula I:.

Deuterated Aminocyclohexyl Ether Compounds And Processes For Preparing Same

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US Patent:
20070088075, Apr 19, 2007
Filed:
Oct 13, 2006
Appl. No.:
11/581225
Inventors:
Doug Chou - Vancouver, CA
Bertrand Plouvier - Vancouver, CA
Peter Pang - Richmond, CA
James Yee - Vancouver, CA
Jeffery Wheeler - Surrey, CA
Aregahegn Yifru - Somerville MA, US
Allen Davidoff - Calgary, CA
Assignee:
Cardiome Pharma Corp. - Vancouver
International Classification:
A61K 31/4015
US Classification:
514424000, 548541000
Abstract:
This invention is directed to deuterated aminocyclohexyl ether compounds and processes for preparing same and methods of using same.
Aregahegn S Yifru from Benicia, CA, age ~52 Get Report