US Patent:
20080038295, Feb 14, 2008
Inventors:
James Baker - Ann Arbor MI, US
Anna Bielinska - Ypsilanti MI, US
Andrzej Myc - Ann Arbor MI, US
Assignee:
Regents of the University of Michigan - Ann Arbor MI
International Classification:
A61K 39/275
A61P 31/00
Abstract:
The present invention relates to methods and compositions for stimulating an immune response. Specifically, the present invention provides methods of inducing an immune response to an orthopox virus (e.g., vaccinia virus) in a subject (e.g., a human subject) and compositions useful in such methods (e.g., a nanoemulsion comprising vaccinia virus). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination) and research applications.