Inventors:
Thomas Lewis - Winchester MA, US
Donald J. Burke - Boston MA, US
Ann M. Szulwach - Middle Village NY, US
International Classification:
A61K 31/555
A61P 35/00
A61P 31/12
A61P 31/04
A61P 9/00
A61P 25/00
Abstract:
Provided herein are compounds for detection, diagnosis and treatment of target tissues or target compositions, including hyperproliferative tissues such as tumors, using sonodynamic and/or photodynamic methods. In particular, photosensitizer and/or sonosensitizer compounds that collect in hyperproliferative tissue are provided.