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Aniko Paul Phones & Addresses

  • Poway, CA
  • Surfside Beach, SC
  • 17 Settlers Way, East Setauket, NY 11733 (631) 751-5663
  • Setauket, NY
  • Albany, NY
  • 109 Briarwood Dr, Ithaca, NY 14850 (607) 257-6610
  • Menlo Park, CA
  • 17 Settlers Way, Setauket, NY 11733

Work

Position: Sales Occupations

Business Records

Name / Title
Company / Classification
Phones & Addresses
Aniko Paul
Owner
Paul, Aniko
Professional Organization
17 Settlers Way, Strongs Neck, NY 11733

Publications

Us Patents

Attenuated Poliovirus

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US Patent:
8066983, Nov 29, 2011
Filed:
Mar 16, 2009
Appl. No.:
12/405068
Inventors:
Eckard Wimmer - E. Setauket NY, US
Jeronimo Cello - Port Jefferson NY, US
Aniko Paul - Setauket NY, US
Hidemi Toyoda - E. Setauket NY, US
Jiang Yin - Port Jefferson NY, US
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
A61K 39/12
C12P 19/33
US Classification:
424 931, 4242171
Abstract:
A novel and stable attenuated poliovirus, which replicates in neuroblastoma cells, is produced by engineering an indigenous replication element (cre), into the 5′ non-translated genomic region and inactivating the native cre element located in the coding region of 2C (mono-crePV). The stably attenuated poliovirus replicates in a neuroblastoma model (Neuro-2atumors) expressing CD155, the poliovirus receptor, and is effective for oncolytic treatment and cure of solid tumors, such as neuroblastoma.

Novel Attenuated Poliovirus

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US Patent:
20120064113, Mar 15, 2012
Filed:
Oct 7, 2011
Appl. No.:
13/269213
Inventors:
Eckard Wimmer - E. Setauket NY, US
Jeronimo Cello - Port Jefferson NY, US
Aniko Paul - Setauket NY, US
Hidemi Toyoda - E. Setauket NY, US
Jiang Yin - Port Jefferson NY, US
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
A61K 35/76
C12N 7/01
A61P 35/00
US Classification:
4241991, 424 932, 4352351
Abstract:
A novel and stable attenuated poliovirus, which replicates in neuroblastoma cells, is produced by engineering an indigenous replication element (cre), into the 5′ non-translated genomic region and inactivating the native cre element located in the coding region of 2C (mono-crePV). The stably attenuated poliovirus replicates in a neuroblastoma model (Neuro-2atumors) expressing CD155, the poliovirus receptor, and is effective for oncolytic treatment and cure of solid tumors, such as neuroblastoma.

Inhibition Of Picornavirus Genome Replication By Interference With Vpg-Nucleotidylylation And Elongation

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US Patent:
61941417, Feb 27, 2001
Filed:
Mar 31, 1999
Appl. No.:
9/282351
Inventors:
Aniko V. Paul - Setauket NY
Eckard Wimmer - E. Setauket NY
Elizabeth Rieder - Port Jefferson Station NY
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
C12Q 100
C12Q 168
US Classification:
435 4
Abstract:
The present invention provides methods of inhibiting picornavirus genome replication in a subject. In particular, methods for interfering with VPg uridylylation and elongation are provided. The methods comprise administering to a subject an effective amount of at least one of VPg, VPg analog, VPg homology or biologically active fragment thereof as well as oligonucleotides, divalent cations, ribonucleotide or deoxyribonucleotide. Also provided are methods of identifying an inhibitor of picornaviral replication which comprise adding a potential inhibitor of picornaviral replication to an in vitro assay and analyzing levels of VPg uridylylation reaction products.

De Novo Cell-Free Synthesis Of Picornavirus

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US Patent:
56747292, Oct 7, 1997
Filed:
Jun 30, 1994
Appl. No.:
8/268679
Inventors:
Eckard Wimmer - Stony Brook NY
Akhteruzzaman Molla - Port Jefferson NY
Aniko V. Paul - Setauket NY
Assignee:
Research Foundation of State University of New York - Albany NY
International Classification:
C12N 700
US Classification:
4352351
Abstract:
A process for the de novo synthesis of a picornavirus using a cell-free medium has been developed. The cell-free medium is prepared from a lysate of mammalian cells from which the nuclei and mitochondria has been removed, endogenous mRNA deactivated and supplemented with nucleoside triphosphates, tRNA, amino acids and precursors necessary for generating proteins. The genomic RNA of the picornavirus or rhinovirus is added to the cell-free medium and after incubation at about 30. degree. C. to 40. degree. C. of from about 4 to 24 hours infectious, mature virus particles are formed.
Aniko V Paul from Poway, CA, age ~85 Get Report