US Patent:
20040191851, Sep 30, 2004
Inventors:
Angelika Reichert - Durham NC, US
Lining Guo - Chapel Hill NC, US
Keith Davis - Durham NC, US
Adel Zayed - Durham NC, US
Robert Ascenzi - Cary NC, US
Douglas Boyes - Chapel Hill NC, US
Rao Mulpuri - Apex NC, US
Neil Hoffman - Chapel Hill NC, US
Susanne Kjemtrup - Chapel Hill NC, US
Carol Hamilton - Apex NC, US
Jeffrey Woessner - Hillsborough NC, US
Jorn Gorlach - Manchester NJ, US
International Classification:
C12Q001/68
C12Q001/42
A01N063/00
C12N009/16
US Classification:
435/021000, 435/196000, 504/117000
Abstract:
The present inventors have discovered that Lipid Transfer Protein (LTP) is essential for plant growth. Specifically, the inhibition of LTP gene expression in plant seedlings results in reduced growth and chlorosis. Thus, LTP is useful as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of herbicides by measuring the activity of an LTP in the presence and absence of a compound, wherein an alteration of LTP activity in the presence of the compound indicates the compound as a candidate for a herbicide.