Angel Pogo Phones & Addresses
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55 1St St, Pelham, NY 10803 (914) 738-3404
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237 Nyac Ave, Pelham, NY 10803 (914) 738-0801
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New Rochelle, NY
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New York, NY
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237 Nyac Ave, Pelham, NY 10803 (914) 772-3810
Work
Position:
Production Occupations
Education
Degree:
Associate degree or higher
Emails
a***o@comcast.net
Publications
Us Patents
Cloning Of Duffy Blood Group Antigen, Gpd
View pageUS Patent:
56836961, Nov 4, 1997
Filed:
Jun 7, 1995
Appl. No.:
8/486670
Inventors:
Angel Oscar Pogo - Pelham NY
Asok Chaudhuri - Rego Park NY
Asok Chaudhuri - Rego Park NY
Assignee:
New York Blood Center, Inc. - New York NY
International Classification:
C07K 14705
A61K 3800
A61K 3800
US Classification:
4241851
Abstract:
gpD protein, the major subunit of the Duffy blood group antigenic system, has been isolated. gpD protein contains the receptor, by which P. vivax enters red cells and causes malaria. gpD has significant sequence homology with human and rabbit interleukin-8 receptors and, therefore, gpD protein likely is a new class of chemoattractant cytokines receptor. gpD protein cDNA has a quasi-total homology with a human hippocampus cDNA clone HHCMF86 and, therefore, gpD protein or a homologous protein may be present as a neuropeptide receptor in brain. gpD protein is present in all red cell progenitors and it may be a receptor for cell proliferation and/or differentiation. gpD protein cDNA identifies in human kidney a mRNA of the same size as the bone marrow. Since the kidney is not and has no potential to become an erythropoietic organ, this putative chemoattractant receptor may have essential renal functions. gpD protein has therapeutic value in the prevention of malaria and in the regulation of erythrocyte, neural and renal functions and can be combined with physiologically acceptable diluents to yield a therapeutic agent suitable for these purposes.
Dna Encoding Duffy 9Pd Protein
View pageUS Patent:
55787142, Nov 26, 1996
Filed:
Oct 21, 1993
Appl. No.:
8/140797
Inventors:
Angel O. Pogo - Pelham NY
Asok Chaudhuri - Rego Park NY
Asok Chaudhuri - Rego Park NY
Assignee:
New York Blood Center, Inc. - New York NY
International Classification:
C07H 2104
C07K 14705
C07K 14705
US Classification:
536 235
Abstract:
gpD protein, the major subunit of the Duffy blood group antigenic system, has been isolated. gpD protein contains the receptor, by which P. vivax enters red cells and causes malaria. gpD has significant sequence homology with human and rabbit interleukin-8 receptors and, therefore, gpD protein likely is a new class of chemoattractant cytokines receptor. gpD protein cDNA has a quasi-total homology with a human hippocampus cDNA clone HHCMF86 and, therefore, gpD protein or a homologous protein may be present as a neuropeptide receptor in brain. gpD protein is present in all red cell progenitors and it may be a receptor for cell proliferation and/or differentiation. gpD protein cDNA identifies in human kidney a mRNA of the same size as the bone marrow. Since the kidney is not and has no potential to become an erythropoietic organ, this putative chemoattractant receptor may have essential renal functions. gpD protein has therapeutic value in the prevention of malaria and in the regulation of erythrocyte, neural and renal functions and can be combined with physiologically acceptable diluents to yield a therapeutic agent suitable for these purposes.