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Andrew V Schally

from Miami Beach, FL
Age ~98
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Also known as:
Andrew Dr Schally, Andrew Victor Schally, Andy Schally, Andrew Null
Phone and address:
3801 Collins Ave APT 1506, Miami, FL 33140
(504) 889-0566
Related to:
David Joseph Burns, 43Anna C Stephan, 42Loris V Rasmussen, 37Maria D Rasmussen, 84Franklin D RasmussenFranklin RasmussenAna Comaru Schally, 81
Connected to:
Mike W Schally, 47Daniel J Schalm, 89Karin D Schalm, 59Roni A Schalman, 69Mary J Schalmo, 73Larry C Schalo, 70Teresa A Schalois, 62Angela B Schalow, 43Kathryn A Schalow, 80Mike Schalow

Andrew Schally Phones & Addresses

  • 3801 Collins Ave APT 1506, Miami Beach, FL 33140 (504) 889-0566
  • 3801 Collins Ave, Miami Beach, FL 33140
  • 8440 Dixie Hwy, Miami, FL 33143
  • 5025 Kawanee Ave, Metairie, LA 70006

Resumes

Resumes

Andrew Schally Photo 1

Research Scientiest

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Location:
Miami, FL
Industry:
Government Administration
Work:
Department of Veterans Affairs
Research Scientiest
Education:
Mcgill University 1952 - 1957
Doctorates, Bachelors, Doctor of Philosophy, Bachelor of Science, Biochemistry
Skills:
Medical Research
Andrew Schally Photo 2

Professor

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Location:
Miami, FL
Work:

Professor

Publications

Wikipedia References

Andrew Schally Photo 3

Andrew Schally

About:
Born:

30 November 1926 • Wilno , Second Polish Republic

Work:
Company:

Tulane University faculty

Position:

President • Prime Minister

Education:
Studied at:

McGill University

Academic degree:

Member of the United States National Academy of Sciences

Area of science:

Endocrinology

Skills & Activities:
Award:

Nobel laureate in Physiology or Medicine • American Nobel laureate • Recipient of the Albert Lasker Award for Basic Medical Research • Prize

Achieved status:

Polish emigrant

Sport:

LIVING

Wikipedia

Andrew Schally

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Andrzej "Andrew" Viktor Schally (born November 30, 1926) is a Polish-born American endocrinologist and Nobel Prize laureate (1977) in medicine, sharing the ...

Us Patents

Antagonistic Analogs Of Gh-Rh Inhibiting Igf-I And -Ii

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US Patent:
7026281, Apr 11, 2006
Filed:
Apr 11, 2000
Appl. No.:
09/547215
Inventors:
Andrew V. Schally - Metairie LA, US
Jozsef Varga - New Orleans LA, US
Marta Zarandi - Szeged, HU
Assignee:
The Administrators of the Tulane Educational Fund - New Orleans LA
International Classification:
A61K 38/00
US Classification:
514 2, 530324, 530317
Abstract:
There is provided a novel series of synthetic analogs of hGH-RH(1–29)NH. These analogs inhibit the activity of endogenous hGH-RH, and therefore prevent the release of growth hormone. The stronger inhibitory potencies of the new analogs, as compared to previously described ones, results from replacement of various amino acids.

Antagonistic Analogs Of Gh Rh (2003)

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US Patent:
7452865, Nov 18, 2008
Filed:
Jul 26, 2004
Appl. No.:
10/566776
Inventors:
Andrew V. Schally - Miami FL, US
Jozsef Varga - Metairie LA, US
Marta Zarandi - Szeged, HU
Ren Zhi Cai - New Orleans LA, US
Assignee:
The Administrare's of the Tulane Educational Fund - New Orleans LA
United States of America by Dept of Veterans Affairs - Washington DC
International Classification:
A61K 38/00
A61K 38/16
A61K 38/25
C07K 14/00
US Classification:
514 12, 514 2, 514 9, 514 10, 514 11, 530324, 530317
Abstract:
There is provided a novel series of synthetic antagonistic analogs of hGH-RH(1-29)NH. These analogs inhibit the activity of endogenous hGH-RH on the pituitary GH-RH receptors, and therefore prevent the release of growth hormone. The analogs also inhibit the proliferation of human cancers through a direct effect on the cancer cells. The higher inhibitory potencies of the new analogs, as compared to previously described ones, results from replacement of various amino acids.

Fluorinated Ghrh Antagonists

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US Patent:
8227405, Jul 24, 2012
Filed:
Sep 17, 2009
Appl. No.:
12/562096
Inventors:
Andrew Schally - Miami Beach FL, US
Jozsef Varga - Miami Beach FL, US
Marta Zarandi - Miami Beach FL, US
Ren Zhi Cai - Miami FL, US
Assignee:
University of Miami - Miami FL
The United States of America as represented by the Department of Veterans Affairs - Washington DC
International Classification:
A61K 38/16
US Classification:
514 11, 424423, 530324
Abstract:
Novel fluorinated synthetic analogs of hGH-RH(1-30)NHthat inhibit the release of growth hormone from the pituitary in mammals as well as inhibit the proliferation of human cancers through a direct effect on the cancer cells, and to therapeutic compositions containing these novel peptides and their use.

Fluorinated Ghrh Antagonists

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US Patent:
8227421, Jul 24, 2012
Filed:
Sep 17, 2009
Appl. No.:
12/562010
Inventors:
Andrew Schally - Miami Beach FL, US
Jozsef Varga - Miami Beach FL, US
Marta Zarandi - Miami Beach FL, US
Ren Zhi Cai - Miami FL, US
Assignee:
University of Miami - Miami FL
The United States of America represented by the Department of Veteran Affairs - Washington DC
International Classification:
A61K 38/16
C07K 14/65
A61F 2/00
US Classification:
514 213, 514 85, 623 111
Abstract:
Novel fluorinated synthetic analogs of hGH-RH(1-30)NHthat inhibit the release of growth hormone from the pituitary in mammals as well as inhibit the proliferation of human cancers through a direct effect on the cancer cells, and to therapeutic compositions containing these novel peptides and their use.

Cardioprotective Effects Of Ghrh Agonists

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US Patent:
8507433, Aug 13, 2013
Filed:
Oct 28, 2010
Appl. No.:
12/914023
Inventors:
Andrew V. Schally - Miami Beach FL, US
Norman L Block - Hollywood FL, US
Joshua Hare - Miami Beach FL, US
Rosemeire Miyuki Kanashiro Takeuchi - Miami FL, US
Assignee:
University of Miami - Miami FL
The United States of America, represented by the Deptartment of Veterans Affairs - Washington DC
International Classification:
A61K 38/25
C07K 14/60
A61P 9/10
US Classification:
514 112, 514 151, 514 213, 530324, 930120
Abstract:
Whether the growth hormone (GH)/Insulin-like growth factor 1(IGF-I) axis exerts cardioprotective effects remains controversial; and the underlying mechanism(s) for such actions are unclear. Here we tested the hypothesis that growth-hormone releasing hormone (GHRH) directly activates cellular reparative mechanisms within the injured heart, in a GH/IGF-I independent fashion. Following experimental myocardial infarction (MI), rats were randomly assigned to receive, during a 4 week period, either placebo (n=14), rat recombinant GH (rrGH, n=8) or JI-38 (n=8; 50 μg/Kg/day), a potent GHRH-agonist. JI-38 did not elevate serum levels of GH or IGF-I, but markedly attenuated the degree of cardiac functional decline and remodeling after injury. In contrast, GH administration markedly elevated body weight, heart weight, circulating GH and IGF-I, but did not offset the decline in cardiac structure and function. Whereas, both JI-38 and GH augmented levels of cardiac precursor cell proliferation, only JI-38 increased anti-apoptotic gene expression.

Agonists Of Growth Hormone Releasing Hormone As Effectors For Survival And Proliferation Of Pancreatic Islets

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US Patent:
20130195807, Aug 1, 2013
Filed:
Jun 3, 2011
Appl. No.:
13/701498
Inventors:
Andrew V. Schally - Miami FL, US
Barbara Ludwig - Dresden, DE
Stefan Bornstein - Dresden, DE
Norman L. Block - Miami FL, US
International Classification:
C07K 14/60
A61K 38/25
A61K 35/12
US Classification:
424 937, 435375, 514 67, 514 69, 514 112, 530399
Abstract:
Agonists of growth hormone releasing hormone promote islet graft growth and proliferation in patients. Methods of treating patients comprise the use of these agonists.

Novel N- And C- Terminal Substituted Antagonistic Analogs Of Gh-Rh

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US Patent:
20130261055, Oct 3, 2013
Filed:
Sep 25, 2010
Appl. No.:
12/890626
Inventors:
Andrew V. Schally - Miami Beach FL, US
Marta Zarandi - Miami Beach FL, US
Jozsef L. Varga - Miami Beach FL, US
Ren Zhi Cai - Miami FL, US
International Classification:
A61K 38/25
A61P 35/00
A61K 38/22
US Classification:
514 81, 530324, 514 112, 514 86, 514 85, 514 91
Abstract:
There is provided a novel series of synthetic analogs of hGH-RH(1-29)NH(SEQ ID NO: 96) and hGH-RH(1-30)NH. Of particular interest are those carrying PhAc, N-Me-Aib, Dca, Ac-Ada, Fer, Ac-Amc, Me-NH-Sub, PhAc-Ada, Ac-Ada-D-Phe, Ac-Ada-Phe, Dca-Ada, Dca-Amc, Nac-Ada, Ada-Ada, or CH—(CH)—CO-Ada, at the N-Terminus and β-Ala, Amc, Apa, Ada, AEA, AEP, ε-Lys(α-NH), Agm, Lys(Oct) or Ahx, at the C-terminus. These analogs inhibit the release of growth hormone from the pituitary in mammals as well as inhibit the proliferation of human cancers, and inhibit the hyperplastic and benign proliferative disorders of various organs, through a direct effect on the cancerous and non-malignant cells. The stronger inhibitory potencies of the new analogs, as compared to previously described ones, result from replacement of various amino acids.

Acceleration Of Wound Healing By Growth Hormone Releasing Hormone And Its Agonists

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US Patent:
20130261058, Oct 3, 2013
Filed:
Sep 16, 2011
Appl. No.:
13/823729
Inventors:
Andrew V. Schally - Miami FL, US
Hippokratis Kiaris - Athens, GR
Norman L. Block - Miami FL, US
Assignee:
University of Miami - Miami FL
U.S. Department of Veterans Affairs - Washington DC
National and Kapodistrian University of Athens - Athens
International Classification:
A61K 38/25
A61K 38/16
US Classification:
514 112
Abstract:
Agonists of growth hormone releasing hormone promote islet graft growth and proliferation in patients. Methods of treating patients comprise the use of these agonists.

Isbn (Books And Publications)

The Hypothalamus and Pituitary in Health and Disease

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Author

Andrew V. Schally

ISBN #

0398025266

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Andrew V Schally from Miami Beach, FL, age ~98 Get Report