US Patent:
20060041111, Feb 23, 2006
Inventors:
Vijay Yajnik - Chestnut Hill MA, US
Charles Paulding - Weymouth MA, US
Andrea McClatchey - Concord MA, US
Daniel Haber - Chestnut Hill MA, US
International Classification:
C07K 14/52
A01K 67/027
C07H 21/02
C12P 21/02
US Classification:
536023100, 530351000, 435069500, 435320100, 435354000, 800018000
Abstract:
The invention relates to a newly identified tumor suppressor gene, designated DOS (for Deleted in Osteosarcoma and alternatively referred to herein as DOCK 3) which has been cloned from human and mouse cells. The DOS nucleic acid and protein molecules and their use in the diagnosing and treating disorders characterized by aberrant DOS molecule expression are described.