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Anatoly N Pinchuk

from Fitchburg, WI
Age ~60
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Also known as:
Andrei Pinchuk, Anatoly Pinchuck
Related to:
Kristine R Caplan, 57Marilyn Caplan, 89Lisa D Marsh, 56Mickey Caplan, 89Jugene Lucht, 81Amanda Marsh, 34
Connected to:
Anna S Pinchuk, 82Joan Pinchuk, 83Judy K Pinchuk, 80Marie Pinchuk, 75Sheena M Pinci, 39Christina M Pinciaro, 34Dorene S Pinciaro, 65Fred W Pinciaro, 104Lisa A Pinciaro, 57Steven E Pincich, 56

Anatoly Pinchuk Phones & Addresses

  • Fitchburg, WI
  • 3025 Whisperwood Dr, Ann Arbor, MI 48105 (734) 222-4795
  • 1373 Mcintyre St, Ann Arbor, MI 48105
  • 42 Mansion Blvd, Delmar, NY 12054 (518) 475-1356
  • 60 Mansion Blvd, Delmar, NY 12054 (518) 475-1356

Publications

Us Patents

Radioiodinated Phospholipid Ether Analogs And Methods Of Using The Same

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US Patent:
6417384, Jul 9, 2002
Filed:
Jul 3, 2001
Appl. No.:
09/898178
Inventors:
Raymond E. Counsell - Ann Arbor MI
Marc A. Longino - Ann Arbor MI
Anatoly N. Pinchuk - Ann Arbor MI
Mark A. Rampy - Gaithersburg MD
Jamey P. Weichert - Fitchburg WI
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
C07F 910
US Classification:
558166, 558169, 424 937
Abstract:
The present invention provides improved radioiodinated phospholipid ether analogs which demonstrate significant tumor avidity and longer plasma half-life than shorter-chain analogs. The radioiodinated phospholipid ether analogs of the present invention provide superior imaging and visualization of neoplastic lesions and tumor-specific cytotoxic cancer therapy.

Fluorescent Phospholipid Ether Compounds And Compositions

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US Patent:
7811548, Oct 12, 2010
Filed:
May 11, 2009
Appl. No.:
12/463970
Inventors:
Anatoly Pinchuk - Madison WI, US
Jamey P. Weichert - Fitchburg WI, US
Marc Longino - Verona WI, US
Irawati Kandela - Madison WI, US
William R. Clarke - Colgate WI, US
Assignee:
Cellectar, Inc. - Madison WI
International Classification:
A61K 51/00
US Classification:
424 177, 424 96, 554 55, 558166, 558169
Abstract:
The invention generally relates to novel fluorescent phospholipid compounds and compositions comprising these compounds. A preferred compound of the present invention has the following structural formula:.

Method For The Synthesis Of Phospholipid Ethers

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US Patent:
7893286, Feb 22, 2011
Filed:
May 30, 2008
Appl. No.:
12/156287
Inventors:
Anatoly Pinchuk - Madison WI, US
Jamey P. Weichert - Fitchburg WI, US
Marc Longino - Verona WI, US
Assignee:
Cellectar, Inc. - Madison WI
International Classification:
C07F 9/02
US Classification:
554 82, 424 165, 424 177, 424 185, 554 80, 554 84, 558166, 558169
Abstract:
Disclosed are improved methods for the synthesis of phospholipid ether analogs and alkyl phosphocholine analogs. The methods allow greater versatility of the reactants used and greater ease in synthesizing alkyl chains of varying length while affording reaction temperatures at room temperature or below. The methods disclosed herein provide reactants and conditions using alkyl halides and organozinc reagents and do not utilize Gringard reactions thus, allowing greater ease of their separation and purity of products. The PLE compounds synthesized by the methods disclosed herein can also be used for synthesizing high specific activity phospholipid ether (PLE) analogs, for use in treatment and diagnosis of cancer.

Compositions Of Phospholipid Ether Boronic Acids And Esters And Methods For Their Synthesis And Use

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US Patent:
8022235, Sep 20, 2011
Filed:
May 30, 2008
Appl. No.:
12/156258
Inventors:
Anatoly Pinchuk - Madison WI, US
Jamey P. Weichert - Fitchburg WI, US
Marc Longino - Verona WI, US
Assignee:
Cellectar, Inc. - Madison WI
International Classification:
C07F 11/00
C07F 7/02
US Classification:
554 77, 514 64
Abstract:
The present invention discloses boronic acids and esters of phospholipid ether analogs and methods for their synthesis and use. The boronic acids and esters of phospholipid ether analogs described herein can be used in treating cancer and in particular can be used in conjunction with radiation therapy, such as external beam radiation therapy and neutron capture therapy to specifically target and kill cancer cells.

Phospholipid Analogs As Diapeutic* Agents And Methods Thereof

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US Patent:
8535641, Sep 17, 2013
Filed:
Mar 2, 2005
Appl. No.:
10/906687
Inventors:
Jamey Weichert - Fitchburg WI, US
Marc Longino - Verona WI, US
Anatoly Pinchuk - Madison WI, US
Assignee:
Cellectar, Inc. - Madison WI
International Classification:
A61K 51/00
A61M 36/14
US Classification:
424 185, 424 111, 424 165, 424 181, 424 91
Abstract:
The present invention provides methods and uses of phospholipid ether analogs as diagnostic and therapeutic agents for numerous cancers.

Phospholipid Ether Analogs As Agents For Detecting And Locating Cancer, And Methods Thereof

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US Patent:
8540968, Sep 24, 2013
Filed:
Dec 20, 2005
Appl. No.:
11/316620
Inventors:
Jamey Weichert - Fitchburg WI, US
Marc Longino - Verona WI, US
Anatoly Pinchuk - Madison WI, US
Assignee:
Cellectar, Inc. - Madison WI
International Classification:
A61K 49/00
US Classification:
424 94, 424 111, 424 165, 424 181, 424 185, 424 91
Abstract:
The present invention provides methods for treating, detecting and locating recurrence of cancer, radiation and chemo insensitive cancer or metastasis of cancer selected from the group consisting of Lung cancer, Adrenal cancer, Melanoma, Colon cancer, Colorectal cancer, Ovarian cancer, Prostate cancer, Liver cancer, Subcutaneous cancer, Squamous cell cancer, Intestinal cancer, Hepatocellular carcinoma, Retinoblastoma, Cervical cancer, Glioma, Breast cancer and Pancreatic cancer in subject using phospholipid ether analogs.

Near Infrared-Fluorescence Using Phospholipid Ether Analog Dyes In Endoscopic Applications

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US Patent:
20080075660, Mar 27, 2008
Filed:
Aug 14, 2007
Appl. No.:
11/891939
Inventors:
Jamey Weichert - Fitchburg WI, US
Marc Longino - Verona WI, US
Anatoly Pinchuk - Madison WI, US
Andreas Muehler - Mountain Lakes NJ, US
Assignee:
Cellectar, LLC - Madison WI
International Classification:
A61K 51/04
A61B 8/12
A61P 43/00
US Classification:
424001770, 424009600
Abstract:
The present invention provides composition and methods of use of phospholipid dyes for use in detection of neoplastic tissue, typically using the routing procedure of endoscopy and methods of optimizing therapy treatment in a subject.

Fluorescent Imaging Of Tumors Using Phospholipid Ether Compounds

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US Patent:
20100284929, Nov 11, 2010
Filed:
May 11, 2009
Appl. No.:
12/463978
Inventors:
Anatoly PINCHUK - Madison WI, US
Jamey P. WEICHERT - Fitchburg WI, US
Marc LONGINO - Verona WI, US
Irawati KANDELA - Madison WI, US
William R. CLARKE - Colgate WI, US
International Classification:
A61K 49/00
US Classification:
424 96
Abstract:
The invention generally relates to the use of novel fluorescent phospholipid ether compounds and compositions comprising these compounds in fluorescence imaging of tumors. A preferred compound of the present invention has the following structural formula:
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Anatoly N Pinchuk from Fitchburg, WI, age ~60 Get Report