Inventors:
- Jacksonville FL, US
Terri Helman FINKEL - Orlando FL, US
Joseph MAZAR - Orlando FL, US
Amy Lynn ROSADO - Orlando FL, US
Jiangfang WANG - Orlando FL, US
Tamarah Jeanette WESTMORELAND - Orlando FL, US
Assignee:
THE NEMOURS FOUNDATION - Jacksonville FL
International Classification:
A61K 35/768
C07K 16/28
A61P 35/00
Abstract:
CD24-positive malignant and benign tumors are treated by administration of a naturally occurring or modified oncolytic Zika virus. Diseases associated with abnormal T cell activation or T cell-mediated autoimmunity, wherein CD24 expression is increased, are also expected to be treated by administration of a naturally occurring or modified oncolytic Zika virus. Also contemplated are compounds and methods for treating and/or preventing Zika virus infection in a subject.
