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Alvin W Kimball

from Sandy, UT
Age ~69
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Also known as:
Alvin C Kimball, Alvin A Kimball, Alvin Kimball Watkins, Al Kimball
Phone and address:
10983 S Sady Ln, Sandy, UT 84070
(801) 231-6217
Related to:
Aaron D Hughes, 72Sasha Kimball, 39Matthew Bilanzich, 39Julie M Kiffer, 45Joshua ShumanSeptember A Kimball, 43Alexandra J Kimball, 34Keli Anne Kimball, 67Deanne KimballCarrie KimballConstance S Kimball, 70Ken R Kimball, 64Constance A Kimball, 47Jonathan R Novick, 62
Connected to:
Aimee L Kimball, 43Alec C Kimball, 33Allison S Kimball, 50Alycia P Kimball, 38Andrea J Kimball, 48Bobbie J Kimball, 72Bobby N Kimball, 64Brandie Kimball, 35Brittany Kimball, 37Cara E Kimball, 61

Alvin Kimball Phones & Addresses

  • 10983 S Sady Ln, Sandy, UT 84070 (801) 231-6217
  • 6922 S 1480 W, West Jordan, UT 84084 (801) 566-2344
  • Salt Lake City, UT
  • 6878 Countrywoods Cir, Midvale, UT 84047
  • 10983 S Sady Ln, Sandy, UT 84070

Publications

Us Patents

Automated Hybridization/Imaging Device For Fluorescent Multiplex Dna Sequencing

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US Patent:
20020012910, Jan 31, 2002
Filed:
Nov 28, 1995
Appl. No.:
08/563462
Inventors:
ROBERT B. WEISS - SALT LAKE CITY UT, US
ALVIN W. KIMBALL - SALT LAKE CITY UT, US
RAYMOND F. GESTELAND - SALT LAKE CITY UT, US
F. MARK FERGUSON - SALT LAKES CITY UT, US
DIANE M. DUNN - WEST VALLEY CIT UT, US
LEONARD J. DI SERA - SALT LAKE CITY UT, US
JOSHUA L. CHERRY - SALT LAKE CITY UT, US
International Classification:
C12Q001/68
G01N021/00
G01N031/00
G01N033/00
C12P019/34
C12M001/38
C12M003/00
G01N027/453
C12M001/36
C12M001/34
G01R001/00
C25B013/00
G01N027/27
G01N027/403
G02B013/18
G02B003/06
C25B011/00
C02F011/00
C25B009/00
C25B009/00
C02F001/40
US Classification:
435/006000, 435/091100, 435/286100, 422/062000, 204/600000, 359/710000
Abstract:
A method is disclosed for automated multiplex sequencing of DNA with an integrated automated imaging hybridization chamber system. This system comprises an hybridization chamber device for mounting a membrane containing size-fractionated multiplex sequencing reaction products, apparatus for fluid delivery to the chamber device, imaging apparatus for light delivery to the membrane and image recording of fluorescence emanating from the membrane while in the chamber device, and programmable controller apparatus for controlling operation of the system. The multiplex reaction products are hybridized with a probe, then an enzyme (such as alkaline phosphatase) is bound to a binding moiety on the probe, and a fluorogenic substrate (such as a benzothiazole derivative) is introduced into the chamber device by the fluid delivery apparatus. The enzyme converts the fluorogenic substrate into a fluorescent product which, when illuminated in the chamber device with a beam of light from the imaging apparatus, excites fluorescence of the fluorescent product to produce a pattern of hybridization. The pattern of hybridization is imaged by a CCD camera component of the imaging apparatus to obtain a series of digital signals. These signals are converted by the controller apparatus into a string of nucleotides corresponding to the nucleotide sequence an automated sequence reader. The method and apparatus are also applicable to other membrane-based applications such as colony and plaque hybridization and Southern, Northern, and Western blots.

Automated Hybridization/Imaging Device For Fluorescent Multiplex Dna Sequencing

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US Patent:
54707102, Nov 28, 1995
Filed:
Oct 22, 1993
Appl. No.:
8/141234
Inventors:
Robert B. Weiss - Salt Lake City UT
Alvin W. Kimball - Salt Lake City UT
Raymond F. Gesteland - Salt Lake City UT
F. Mark Ferguson - Salt Lake City UT
Diane M. Dunn - West Valley City UT
Leonard J. Di Sera - Salt Lake City UT
Joshua L. Cherry - Salt Lake City UT
Assignee:
University of Utah - Salt Lake City UT
International Classification:
C12Q 168
US Classification:
435 6
Abstract:
A method is disclosed for automated multiplex sequencing of DNA with an integrated automated imaging hybridization chamber system. This system comprises an hybridization chamber device for mounting a membrane containing size-fractionated multiplex sequencing reaction products, apparatus for fluid delivery to the chamber device, imaging apparatus for light delivery to the membrane and image recording of fluorescence emanating from the membrane while in the chamber device, and programmable controller apparatus for controlling operation of the system. The multiplex reaction products are hybridized with a probe, then an enzyme (such as alkaline phosphatase) is bound to a binding moiety on the probe, and a fluorogenic substrate (such as a benzothiazole derivative) is introduced into the chamber device by the fluid delivery apparatus. The enzyme converts the fluorogenic substrate into a fluorescent product which, when illuminated in the chamber device with a beam of light from the imaging apparatus, excites fluorescence of the fluorescent product to produce a pattern of hybridization. The pattern of hybridization is imaged by a CCD camera component of the imaging apparatus to obtain a series of digital signals.
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Alvin W Kimball from Sandy, UT, age ~69 Get Report