Alton Meister

43352103, Jun 15, 1982

Feb 11, 1981

6/233564

Alton Meister - New York NY
Joanne M. Williamson - Roosevelt Island NY

Cornell Research Foundation - Ithaca NY

C12P 1312

435113

L-2-oxothiazolidine-4-carboxylate, a sulfur analog of 5-oxoproline, is cleaved by the enzyme 5-oxo-L-prolinase to form cysteine, thus providing the basis for a cysteine delivery system by the addition of L-2-oxothiazolidine-4-carboxylate to base amino acid solutions or by injecting it directly into in vivo cells.

54648254, Nov 7, 1995

Apr 12, 1994

8/226409

Mary Anderson - New York NY
Alton Meister - New York NY
Ellen J. Levy - Brooklyn NY

Cornell Research Foundation, Inc. - Ithaca NY

A61K 3800
C07K 500
C07K 700
C07K 1700

514 18

The preparation and use of N-acyl glutathione monoalkyl esters to provide increased intracellular levels of glutathione or glutathione equivalents, e. g. N-acyl glutathione or glutathione monoalkyl esters.

57473293, May 5, 1998

Dec 5, 1994

8/350325

Alton Meister - New York NY
Mary E. Anderson - New York NY

Cornell Research Foundation, Inc. - Ithaca NY

C12N 120
C12N 900
C12D 2106
C07H 2104

43525233

The nucleotide cDNA sequence for the light subunit of gamma glutamylcysteine synthetase, and the amino acid sequence for this subunit, are disclosed.

47846852, Nov 15, 1988

Jul 1, 1987

7/068306

Alton Meister - New York NY

Cornell Research Foundation, Inc. - Ithaca NY

A01N 3700

71106

Substantially pure alkyl monoesters of glutathione, the ester being of the glycine carboxylic acid, and use thereof to increase cellular levels of glutathione.

61271659, Oct 3, 2000

Feb 13, 1995

8/387117

Mary Elizabeth Anderson - New York NY
Alton Meister - New York NY

Cornell Research Foundation, Inc. - Ithaca NY

C12N 121
C12N 900
C12N 1563
C07H 2104

4352523

The present invention relates to recombinant rat kidney glutathione synthetase. This enzyme can be used to prepare glutathione analogs, and to raise antibodies against glutathione synthetase. The present invention further relates to a DNA molecule encoding rat kidney glutathione synthetase. The DNA molecule is useful for detecting the presence of the glutathione synthetase gene in animals, and for modifying cell and mammal glutathione production. The DNA molecule can also be used to construct models for evaluation of potential therapies.

46650822, May 12, 1987

Jun 27, 1985

6/750043

Alton Meister - New York NY
Joanne M. Williamson - Roosevelt Island NY

Cornell Research Foundation - Ithaca NY

A61K 31425
A61K 3123

514365

L-2-oxothiazolidine-4-carboxylate, a sulfur analog of 5-oxoproline, is cleaved by the enzyme 5-oxo-L-prolinase to form cysteine, thus providing the basis for a cysteine delivery system by the addition of L-2-oxothiazolidine-4-carboxylate to base amino acid solutions or by injecting it directly into in vivo cells.

48793701, Nov 7, 1989

Jul 27, 1988

7/225672

Alton Meister - New York NY

Cornell Research Foundation, Inc. - Ithaca NY

C07K 508

530331

Substantially pure alkyl monoesters of glutathione, the ester being of the glycine carboxylic acid, and use thereof to increase cellular levels of glutathione.

47104899, Dec 1, 1987

Jan 10, 1986

6/817696

Alton Meister - New York NY

Cornell Research Foundation, Inc. - Ithaca NY

A61K 3702
C07K 508

514 18

Substantially pure alkyl monoesters of glutathione, the ester being of the glycine carboxylic acid, and use thereof to increase cellular levels of glutathione.