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Alexander A Poulev

from Highland Park, NJ
Age ~70
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Also known as:
Alexander A Pouleva, Alex Poulev
Phone and address:
168 Exeter St, New Brunswick, NJ 08904
(732) 777-9019
Related to:
Reneta B Pouleva, 74Katia A Pouleva, 40
Connected to:
Emlyn Pouli, 33Victoria L Poulides, 52Alex M Poulin, 35Alexandra M Poulin, 37Angeline L Poulin, 51Annie Poulin, 52Ashlee J Poulin, 43Austin C Poulin, 32Brett A Poulin, 39Denie A Poulin, 45

Alexander Poulev Phones & Addresses

  • 168 Exeter St, Highland Park, NJ 08904 (732) 777-9019
  • 18 Exeter St, Highland Park, NJ 08904
  • Belmont, CA
  • 168 Exeter St, Highland Park, NJ 08904

Publications

Us Patents

Methods Of Administering Gaultherin-Containing Compositions

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US Patent:
7033618, Apr 25, 2006
Filed:
Jan 8, 2003
Appl. No.:
10/338312
Inventors:
David M. Ribnicky - Plainsboro NJ, US
Alexander A. Poulev - Highland Park NJ, US
Ilya Raskin - Manalapan NJ, US
Assignee:
Rutgers University, The State University of New Jersey - New Brunswick NJ
International Classification:
A61K 35/78
US Classification:
424725
Abstract:
The present disclosure provides methods for obtaining gaultherin, a natural salicylate derivative, from plant tissue. The methods involve preventing the hydrolysis of the gaultherin in the plant tissue by disrupting the plant tissue under solvent conditions lacking a drying agent. The disclosure further provides various forms of plant-derived gaultherin, including alcoholic extracts, aqueous solutions and dried preparations, all suitable for use as a natural aspirin substitute. Moreover, the disclosure provides methods of using gaultherin-containing compositions to increase serum salicylic acid, to treat cancer cells, to treat cardiovascular (e. g. , cardiopulmonary) conditions, to treat anti-inflammatory responses, and to inhibit cyclooxygenase.

Recovery Of Gaultherin From Plants

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US Patent:
20020031562, Mar 14, 2002
Filed:
Jun 21, 2001
Appl. No.:
09/887766
Inventors:
David Ribnicky - Monmouth Junction NJ, US
Alexander Poulev - Highland Park NJ, US
Ilya Raskin - Manalapan NJ, US
International Classification:
A61K035/78
C07H013/02
US Classification:
424/769000, 536/119000
Abstract:
The present invention provides methods for obtaining gaultherin, a natural salicylate derivative, from plant tissue. The methods involve preventing the hydrolysis of the gaultherin in the plant tissue by disrupting the plant tissue under solvent conditions lacking a drying agent. The invention further provides various forms of plant-derived gaultherin, including alcohol extracts, aqueous solutions and dried preparations, all suitable for use as a natural aspirin substitute.

Elicited Plant Products

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US Patent:
20020132021, Sep 19, 2002
Filed:
Aug 13, 2001
Appl. No.:
09/929328
Inventors:
Ilya Raskin - Manalapan NJ, US
Alexander Poulev - Highland Park NJ, US
International Classification:
A61K035/78
US Classification:
424/773000
Abstract:
Intact living plants or plant parts are contacted with water to extract from the plant or plant part exuded chemical compounds, with the extracted chemical compounds subsequently being recovered from the water. The plant is treated with an elicitor or inducer to initiate or increase production of a chemical compound. The roots may be harvested for recovery of the chemical compounds. Valuable substances exuded from or onto a plant surface, such as a plant cuticle or the root of a plant, can be identified as biologically active. Libraries of substances exuded or secreted from various plant species can be elicited or induced to produce one or more of such substances.

Compounds From An Extract Of Artemisia And Methods For Treating Disorders

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US Patent:
20070224301, Sep 27, 2007
Filed:
Mar 21, 2006
Appl. No.:
11/385524
Inventors:
David Ribnicky - North Branch NJ, US
Alexander Poulev - Highland Park NJ, US
William Cefalu - Baton Rouge LA, US
Ilya Raskin - Manalapan NJ, US
International Classification:
A61K 36/282
A61K 31/7048
A61K 31/22
US Classification:
424740000, 514027000, 514548000
Abstract:
This invention comprises an extract of that can be used for the treatment and prevention of diabetes, diabetic complications, metabolic syndrome and other comorbidities that share the underlying commonality of insulin resistance. The invention includes the identity of six compounds from the extract that contribute to the activity of the extract by inhibiting protein tyrosine phosphatase-1B (PTP-1B) activity, phosphoenolpyruvate carboxykinase (PEPCK) gene expression or aldose reductase activity (ALR2). The compounds include 4,5-Di-O-caffeoylquinic acid, davidigenin, 6-demethoxycapillarisin, 2′,4-dihydroxy-4′-methoxydihydrochalcone, 2′,4′-dihydroxy-4-methoxdihydrochalcone and sakuranetin.

Phenethylisothiocyanate Nutraceutical Compositions And Methods

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US Patent:
6348220, Feb 19, 2002
Filed:
Apr 9, 1999
Appl. No.:
09/289015
Inventors:
David M. Ribnicky - Plainsboro NJ
Alexander A. Poulev - Highland Park NJ
Ilya Raskin - Manalapan NJ
Assignee:
Rutgers, the State University of New Jersey - New Brunswick NJ
International Classification:
A61K 3578
US Classification:
424725, 424755, 424776
Abstract:
The present invention provides methods for obtaining phenethyl isothiocyanate (PEITC), a natural glucosinylate derivative, from plant tissue. The methods involve selection of plant tissue naturally rich in PEITC, followed by aqueous extraction under conditions that promote optimal release of PEITC from the tissue. The invention further provides plant preparations containing significant quantities of PEITC and nutraceutical formulations comprising these preparations.
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Alexander A Poulev from Highland Park, NJ, age ~70 Get Report