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Alex Toker

from Dedham, MA
Age ~59
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Also known as:
Toker Iskander, Toker Alex, Alex R
Related to:
Joan Degraaf
Connected to:
Cem T Toker, 67Kerwyn S Tokeshi, 46Melih T Tokgozoglu, 59Virginie W Tokha, 44Alan P Tokheim, 64Ashish Tokhi, 48Dorana M Tokhi, 46Fareed Tokhi, 46Marva Tokhi, 35Missak Tokhmanian, 38

Alex Toker Phones & Addresses

  • Dedham, MA
  • 5 Alton Ct, Brookline, MA 02446
  • 5 Alton Ct #6, Brookline, MA 02446
  • Boston, MA
  • 219 Brighton St, Belmont, MA 02478 (617) 794-0340
  • Cambridge, MA
  • Arlington, MA
  • Swampscott, MA
  • 68 Jamaica St #3, Jamaica Plain, MA 02130

Publications

Us Patents

Nfat Transcription Factors In Tumor Progression

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US Patent:
20050100897, May 12, 2005
Filed:
Mar 31, 2003
Appl. No.:
10/403165
Inventors:
Alex Toker - Brookline MA, US
Sebastien Jauliac - Paris, FR
International Classification:
C12Q001/68
US Classification:
435006000
Abstract:
The present invention provides therapeutic and diagnositic methods for neoplasia treatment. The invention also relates to determining the prognosis of a neoplasia or determining a treatment protocal. Further features of the invention are methods for identifying NFAT target genes that promote neoplasia progression.

Degradation Of Akt By Conjugation Of Atp-Competitive Akt Inhibitor Gdc-0068 With E3 Ligase Ligands And Methods Of Use

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US Patent:
20220226481, Jul 21, 2022
Filed:
Apr 8, 2020
Appl. No.:
17/601640
Inventors:
- Boston MA, US
Tinghu Zhang - Brookline MA, US
Eric Fischer - Chestnut Hill MA, US
Katherine Donovan - Boston MA, US
Emily Erickson - Brookline MA, US
Alex Toker - Dedham MA, US
Assignee:
DANA-FARBER CANCER INSTITUTE, INC. - Boston MA
BETH ISRAEL DEACONESS MEDICAL CENTER, INC. - Boston MA
International Classification:
A61K 47/55
A61K 47/54
A61K 31/337
A61P 35/00
Abstract:
Disclosed are bifunctional compounds comprising a GDC-0068 analog that binds AKT isoforms AKT1, 2 and 3, pharmaceutical compositions, and methods for treating diseases or conditions mediated by dysfunctional AKT activity.
Control profile
Alex Toker from Dedham, MA, age ~59 Get Report