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Alessandro Grattoni

from Houston, TX
Age ~46
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Related to:
Juan P Sanchez, 39Gema Rodriguez, 43Gabriela Sanchez, 53Karla M RiveroJauni L Coonie, 46Ruben M Lopez, 74Adalberto Sanchez, 50Maria Sanchez, 69Rachel T Frederick, 63
Connected to:
Aline D Gratton, 55Amanda R Gratton, 40Daniel Gratton, 40Eric J Gratton, 42Geoffrey M Gratton, 56Joann A Gratton, 48Jodi O Gratton, 62Judy R Gratton, 77Kara L Gratton, 53Kelly M Gratton, 53

Alessandro Grattoni Phones & Addresses

  • 6200 Wickersham Ln, Houston, TX 77057
  • Spring, TX

Work

Company: Houston methodist Oct 2010 Position: Professor

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Polytechnic of Turin 2006 to 2009 Specialities: Biomedical Engineering

Skills

Life Sciences • Space Science • Drug Delivery • Nanotechnology • Research

Industries

Research

Resumes

Resumes

Alessandro Grattoni Photo 1

Professor

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Location:
Houston, TX
Industry:
Research
Work:
Houston Methodist
Professor
Education:
Polytechnic of Turin 2006 - 2009
Doctorates, Doctor of Philosophy, Biomedical Engineering Polytechnic of Turin
Masters, Mechanical Engineering
Skills:
Life Sciences
Space Science
Drug Delivery
Nanotechnology
Research

Publications

Us Patents

Nanochanneled Device And Related Methods

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US Patent:
8632510, Jan 21, 2014
Filed:
Apr 13, 2010
Appl. No.:
13/264069
Inventors:
Mauro Ferrari - Houston TX, US
Xuewu Liu - Sugar Land TX, US
Alessandro Grattoni - Houston TX, US
Randy Goodall - Austin TX, US
Lee Hudson - Elgin TX, US
Assignee:
The Board of Regents of the University of Texas System - Austin TX
The Ohio State University Research Foundation - Columbus OH
International Classification:
A61M 37/00
US Classification:
60428801, 60428802, 604513, 6048911
Abstract:
A capsule configured for in vivo refilling of a thereapeutic agent. In certain embodiments, the capsule may contain methotrexate.

Nanochanneled Device And Related Methods

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US Patent:
20100152699, Jun 17, 2010
Filed:
Nov 13, 2009
Appl. No.:
12/618233
Inventors:
Mauro Ferrari - Houston TX, US
Xuewu Liu - Sugar Land TX, US
Alessandro Grattoni - Houston TX, US
Daniel Fine - Austin TX, US
Randy Goodall - Austin TX, US
Sharath Hosali - Austin TX, US
Ryan Medema - Pflugerville TX, US
Lee Hudson - Elgin TX, US
Assignee:
The Board of Regents of the University of Texas System - Austin TX
The Ohio State University Research Foundation - Columbus OH
International Classification:
A61M 37/00
F16L 3/01
B32B 38/10
C23F 1/00
US Classification:
604500, 137561 R, 156257, 216 37
Abstract:
A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel.

Quality Control Method And Micro/Nano-Channeled Devices

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US Patent:
20110137596, Jun 9, 2011
Filed:
Apr 28, 2009
Appl. No.:
12/990411
Inventors:
Alessandro Grattoni - Houston TX, US
Mauro Ferrari - Houston TX, US
Assignee:
The Board of Regents of The University of Texas System - Austin TX
International Classification:
G06F 19/00
US Classification:
702 84
Abstract:
Embodiments of the present invention comprise a quality control system and method for testing micro- or nano-channeled devices. The system and method can utilize a pressure-driven gas flow for the detection and quantification of structural defects. The test method and system are non-destructive and allow defects to be detected and classified quickly based on measured factors, such as mass flow rate for a given pressure differential.

Nanochanneled Device And Related Methods

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US Patent:
20130131629, May 23, 2013
Filed:
May 19, 2011
Appl. No.:
13/698926
Inventors:
Alessandro Grattoni - Houston TX, US
Aman P. Mann - La Jolla CA, US
Sharath Hosali - Austin TX, US
Randy Goodall - Austin TX, US
Lee Hudson - Elgin TX, US
Assignee:
The Board of Regents of the Unversity of Texas System - Austin TX
International Classification:
A61M 37/00
US Classification:
604500, 604 9301, 604257
Abstract:
Apparatus and methods of delivering a therapeutic agent using an implant comprising a nanochannel delivery device.

Nanochanneled Device And Related Methods

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US Patent:
20130240483, Sep 19, 2013
Filed:
May 2, 2013
Appl. No.:
13/875871
Inventors:
The Board of Regents of the University of Texas System - , US
Alessandro GRATTONI - Houston TX, US
Daniel FINE - Austin TX, US
Randy GOODALL - Austin TX, US
Sharath HOSALI - Austin TX, US
Ryan MEDEMA - Pflugerville TX, US
Lee HUDSON - Elgin TX, US
Assignee:
The Ohio State University Research Foundation - Columbus OH
The Board of Regents of the University of Texas System - Austin TX
International Classification:
A61M 37/00
US Classification:
216 83
Abstract:
A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel.

Stabilized Drug Formulations And Methods Of Loading Drug Delivery Implants

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US Patent:
20230023802, Jan 26, 2023
Filed:
Dec 7, 2020
Appl. No.:
17/756859
Inventors:
- Houston TX, US
Fernanda Paola Pons Faudoa - Houston TX, US
Alessandro Grattoni - Houston TX, US
Assignee:
THE METHODIST HOSPITAL SYSTEM - Houston TX
International Classification:
A61K 9/00
A61K 31/675
A61K 47/22
A61K 9/08
Abstract:
The present disclosure provides solid drug formulations, in particular to stabilized formulations of phosphonamidate-containing drugs, as well as methods for loading drug delivery devices with solid formulations.

Method And Apparatus For The Fail-Safe Termination Of In Vivo Drug Delivery From An Implantable Drug Delivery System

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US Patent:
20180280617, Oct 4, 2018
Filed:
Oct 19, 2016
Appl. No.:
15/769401
Inventors:
- Houston TX, US
Robert Lyle Hood - Houston TX, US
Alessandro Grattoni - Houston TX, US
International Classification:
A61M 5/168
A61M 5/142
A61K 9/00
A61K 47/02
A61K 47/34
Abstract:
A method for the fail-safe termination of in vivo drug delivery from an implantable drug delivery system, the method comprising: providing an implantable drug delivery system comprising: a housing having a reservoir for containing a drug, and a port for dispensing the drug to a patient; and an emergency deactivation unit disposed between the reservoir and the port, the emergency deactivation unit comprising a composite structure comprising a biocompatible ferromagnetic mesh open to fluid flow and a hydrophobic meltable material, the hydrophobic meltable material comprising at least one hole therein for enabling a fluid to pass through the hydrophobic meltable material; implanting the implantable drug delivery system within a patient; enabling the drug to flow from the reservoir, through the at least one hole in the hydrophobic meltable material and out the port; and when drug flow is to be terminated, applying a magnetic field to the composite structure, such that a current is induced in the ferromagnetic mesh which heats the ferromagnetic mesh and melts the hydrophobic meltable material, thereby closing the at least one hole in the hydrophobic meltable material and blocking drug delivery to the patient.

Nanochanneled Device And Related Methods

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US Patent:
20150246174, Sep 3, 2015
Filed:
Mar 16, 2015
Appl. No.:
14/658561
Inventors:
- Austin TX, US
- Columbus OH, US
Alessandro Grattoni - Houston TX, US
Randy Goodall - Austin TX, US
Lee Hudson - Elgin TX, US
Assignee:
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM - Austin TX
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION - Columbus OH
International Classification:
A61M 5/00
Abstract:
A capsule configured for in vivo refilling of a therapeutic agent. In certain embodiments, the capsule may contain methotrexate.
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Alessandro Grattoni from Houston, TX, age ~46 Get Report