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Alain R Thierry

from Bethesda, MD
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Connected to:
Antoinette Thierry, 35Antonio C Thierry, 50Brayanna E Thierry, 38Carl W Thierry, 59Carol A Thierry, 71Demarcus Thierry, 36Donald J Thierry, 73Frederic Thierry, 30Hector M Thierry, 60Henk D Thierry, 78

Alain Thierry Phones & Addresses

  • 4970 Battery Ln, Bethesda, MD 20814
  • Washington, DC

Publications

Us Patents

Method Of Making Liposomal Oligodeoxynucleotide Compositions

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US Patent:
56657102, Sep 9, 1997
Filed:
Dec 10, 1993
Appl. No.:
8/165000
Inventors:
Aquilur Rahman - Gaithersburg MD
Alain Thierry - Washington DC
Anatoly Dritschilo - Bethesda MD
Assignee:
Georgetown University - Washington DC
International Classification:
C07H 100
C07H 2100
US Classification:
514 44
Abstract:
A liposome, which contains an oligodeoxynucleotide or an analog thereof.

Method For The Liposomal Delivery Of Nucleic Acids

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US Patent:
59086351, Jun 1, 1999
Filed:
Aug 5, 1994
Appl. No.:
8/286730
Inventors:
Alain Thierry - Bethesda MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:
A61K 9127
US Classification:
424450
Abstract:
The present invention is directed to a liposomal preparation which is based on specific lipid components. The liposomal compounds are also combined with nucleic acids, forming nucleic acid-liposomal compounds. These compounds are useful in drug delivery, where specific therapeutic nucleic acids are used in the liposomes. The specific lipid components of the present invention provide a highly efficient and stable delivery system for nucleic acids. Consequently, the liposomal preparations are suitable for use in gene therapy.

Liposomally Encapsulated Nucleic Acids Having High Entrapment Efficiencies, Method Of Manufacturer And Use Thereof For Transfection Of Targeted Cells

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US Patent:
57561222, May 26, 1998
Filed:
Jun 7, 1995
Appl. No.:
8/483090
Inventors:
Alain Thierry - Bethesda MD
Anatoly Dritschilo - Bethesda MD
Assignee:
Georgetown University - Washington DC
International Classification:
A61K 9127
US Classification:
424450
Abstract:
An improved method for encapsulating high molecular weight nucleic acids in liposomes, which provides for high nucleic acid entrapment efficiencies, is provided. The resulting compositions provide enhanced in vitro and in vivo transfection and are useful, for example, in producing cell lines expressing a desired nucleic acid sequence.

Method Of Encapsulating Anthracycline In Liposomes

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US Patent:
55609236, Oct 1, 1996
Filed:
Sep 28, 1994
Appl. No.:
8/314543
Inventors:
Aquilur Rahman - Gaithersburg MD
Alain Thierry - Washington DC
Anatoly Dritschilo - Bethesda MD
Assignee:
Georgetown University - Washington DC
International Classification:
A61K 9127
US Classification:
424450
Abstract:
A method of preparing a liposomal anthracycline glycoside composition, which entails forming cardiolipin-containing liposomes by drying a lipid mixture containing cardiolipin, and then introducing an aqueous solution, and mixing the cardiolipin-containing liposomes with a solution of anthracycline glycoside.
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Alain R Thierry from Bethesda, MD Get Report