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Akiko Eguchi

from San Diego, CA
Age ~52
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Connected to:
Aya Eguchi, 52Harry T Eguchi, 103Kazuo Eguchi, 56Kenichi Eguchi, 60Noboru Eguchi, 63Rhonda A Eguchi, 57Takehisa Eguchi, 62Miguel A Eguez, 56Efrain E Egui, 64Andrea Eguia, 36

Akiko Eguchi Phones & Addresses

  • San Diego, CA
  • 17191 Bernardo Center Dr, San Diego, CA 92128

Work

Company: University of california, san diego Oct 2011 Position: Project scientist

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Osaka University, Japan 1997 to 2001

Skills

Fusogenic Liposome Preparation • Phage Display • Isolation of Pre Adipocyte and Adipocyte • Histology • Drug Discovery • Sendai Virus Amplification • Microinjection • Antibody Purification • Making Tissue Section By Cryostat • Mice Imaging • Generate Mouse Cancer/Disease Model • Small Surgery In Mouse • Flow Cytometry • Cell Separation By Macs • Stem Cells • Protein Expression • Baculovirus • Confocal Microscopy • Lipid Extraction • Site Directed Mutagenesis • Protein Purification • Biotechnology • Fplc • Fluorescence Microscopy • Biochemistry • Dna Extraction • Molecular Biology • Rna Isolation • Transfection With Dna/Sirna/Mirna/Mrna • Cell Biology • Immunofluorescence • Western Blotting • Electron Microscopy • Elisa • Produce of Monoclonal/Polyclonal Antibod... • Mouse Intravenous Injection • Dna • Transfection • Antibodies • Pcr • Cell Based Assays • Life Sciences • Microscopy • Qpcr • Cancer • Hplc • Sds Page • Microbiology • Tissue Culture • Molecular Cloning

Industries

Research

Resumes

Resumes

Akiko Eguchi Photo 1

Project Scientist

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Location:
San Diego, CA
Industry:
Research
Work:
University of California, San Diego
Project Scientist
Ucsd/Hhmi 2005 - Sep 2011
Postdoctoral Fellow By Jsps ~ Project Scientist
Life Science Center of Tsukuba Advanced Research Alliance Apr 2006 - Mar 2011
Visiting Researcher
Aist 2001 - 2005
Postdoctoral Fellow By Japan Science and Technology Corporation
Osaka University 1997 - 2001
Graduate Student
Education:
Osaka University, Japan 1997 - 2001
Doctorates, Doctor of Philosophy Osaka University, Japan 1995 - 1997
Masters Gunma University 1991 - 1995
Bachelors, Engineering Osaka University, Japan 1988 - 1988
Doctorates, Doctor of Philosophy Osaka University
Skills:
Fusogenic Liposome Preparation
Phage Display
Isolation of Pre Adipocyte and Adipocyte
Histology
Drug Discovery
Sendai Virus Amplification
Microinjection
Antibody Purification
Making Tissue Section By Cryostat
Mice Imaging
Generate Mouse Cancer/Disease Model
Small Surgery In Mouse
Flow Cytometry
Cell Separation By Macs
Stem Cells
Protein Expression
Baculovirus
Confocal Microscopy
Lipid Extraction
Site Directed Mutagenesis
Protein Purification
Biotechnology
Fplc
Fluorescence Microscopy
Biochemistry
Dna Extraction
Molecular Biology
Rna Isolation
Transfection With Dna/Sirna/Mirna/Mrna
Cell Biology
Immunofluorescence
Western Blotting
Electron Microscopy
Elisa
Produce of Monoclonal/Polyclonal Antibodies In Animals
Mouse Intravenous Injection
Dna
Transfection
Antibodies
Pcr
Cell Based Assays
Life Sciences
Microscopy
Qpcr
Cancer
Hplc
Sds Page
Microbiology
Tissue Culture
Molecular Cloning

Publications

Us Patents

Transducible Delivery Of Sirna By Dsrna Binding Domain Fusions To Ptd/Cpps

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US Patent:
8273867, Sep 25, 2012
Filed:
Feb 9, 2007
Appl. No.:
12/278739
Inventors:
Steven F. Dowdy - La Jolla CA, US
Jehangir S. Wadia - San Diego CA, US
Bryan Meade - San Diego CA, US
Akiko Eguchi - San Diego CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12N 15/11
C07H 21/02
US Classification:
536 245, 514 44 A, 530300
Abstract:
The disclosure provides fusion polypeptides and constructs useful in delivering anionically charged nucleic acid molecules including diagnostics and therapeutics to a cell or subject. The fusion constructs include a protein transduction domain and a nucleic acid binding domain, or a protein transduction domain and a nucleic acid that is coated with one or more nucleic acid binding domains sufficient to neutralize an anionic charge on the nucleic acid. Also provided are methods of treating disease and disorders such as cell proliferative disorders.

Transducible Delivery Of Nucleic Acids Using Modified Dsrna Binding Domains

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US Patent:
20120101045, Apr 26, 2012
Filed:
May 7, 2010
Appl. No.:
13/319326
Inventors:
Steven F. Dowdy - La Jolla CA, US
Akiko Eguchi - San Diego CA, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA
International Classification:
A61K 38/17
A61P 35/00
C12N 5/071
C07K 14/00
C07K 14/47
US Classification:
514 193, 530300, 514 209, 530358, 530322, 435375
Abstract:
The disclosure provides fusion polypeptides and constructs useful in delivering anionically charged nucleic acid molecules including diagnostics and therapeutics to a cell or subject. The fusion constructs include a protein transduction domain and a nucleic acid binding domain, or a protein transduction domain and a nucleic acid that is coated with one or more nucleic acid binding domains sufficient to neutralize an anionic charge on the nucleic acid. Also provided are methods of treating disease and disorders such as cell proliferative disorders.

Detecting And Treating Liver Damage

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US Patent:
20150247149, Sep 3, 2015
Filed:
Jan 28, 2015
Appl. No.:
14/607721
Inventors:
- Oakland CA, US
Akiko Eguchi - San Diego CA, US
International Classification:
C12N 15/113
C07K 16/40
G01N 33/569
Abstract:
The invention provides a method of detecting, monitoring, assessing and treating non-alcoholic fatty acid liver disease (NAFLD) and associated liver damage in a subject comprising measuring the amount of hepatocyte-derived circulating extracellular vesicles (EVs) and/or microparticle (MPs) in the bodily sample, or the expression level or activity of at least one biomarker expressed or detected in the EVs and/or MPs. The increased amount of EVs or MPs in the bodily sample and/or the increased expression or detection level of the biomarker of interest correlate with the degree or severity of NAFLD, NASH, liver fibrosis, or other associated liver damage, which can be associated with angiogenesis. Prevention and treatment of NAFLD, NASH, liver fibrosis or associated liver damage by reducing EVs or MPs, or targeting the biomarkers expressed in the EVs or MPs are also provided.
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Akiko Eguchi from San Diego, CA, age ~52 Get Report