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Ake P Elhammer

from Kalamazoo, MI
Age ~76

Ake Elhammer Phones & Addresses

  • 9123 Highland View Dr, Kalamazoo, MI 49009 (269) 544-0458
  • 6233 Countrywood Ct, Kalamazoo, MI 49009
  • 9123 Highland View Dr, Kalamazoo, MI 49009

Work

Company: Aureogen , inc Position: Chief executive officer

Skills

Drug Discovery • Clinical Development • Biotechnology • Biochemistry • Lifesciences • Drug Development • Pharmaceutical Industry • Protein Chemistry • Technology Transfer • Immunology • Life Sciences • Biopharmaceuticals

Industries

Biotechnology

Resumes

Resumes

Ake Elhammer Photo 1

Ake Elhammer

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Location:
Kalamazoo, MI
Industry:
Biotechnology
Work:
Aureogen , Inc
Chief Executive Officer

Aureogen , Inc
Executive Vice President
Skills:
Drug Discovery
Clinical Development
Biotechnology
Biochemistry
Lifesciences
Drug Development
Pharmaceutical Industry
Protein Chemistry
Technology Transfer
Immunology
Life Sciences
Biopharmaceuticals

Publications

Us Patents

Assay For Inositol Phosphorylceramide Synthase Activity

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US Patent:
7659088, Feb 9, 2010
Filed:
May 22, 2007
Appl. No.:
11/805010
Inventors:
Ake Elhammer - Kalamazoo MI, US
Assignee:
AureoGen Biosciences, Inc. - Kalamazoo MI
International Classification:
C12Q 1/48
C12N 9/12
G01N 21/64
US Classification:
435 15, 435194, 436172
Abstract:
Disclosed is a simple and reproducible method for assaying inositol phosphorylceramide synthase activity that employs a fluorescence resonance energy transfer pair for measuring enzyme activity. The invention also includes a novel method for identifying IPC synthase inhibitors.

High-Efficiency Assay For Protein Mannosyl Transferases

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US Patent:
20030017520, Jan 23, 2003
Filed:
May 13, 2002
Appl. No.:
10/144172
Inventors:
Ake Elhammer - Kalamazoo MI, US
Ference Kezdy - Kalamazoo MI, US
International Classification:
C12Q001/48
US Classification:
435/015000
Abstract:
The present invention provides novel procedures to assay the activity of protein mannosyl transferases ability to catalyze the transfer of mannose from the donor sugar lipid dolichyl phosphoryl mannose to the acceptor peptide and agents or compounds that inhibit the activity of protein mannosyl transferases.

Methods Of Treating Infection

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US Patent:
20090124539, May 14, 2009
Filed:
Sep 26, 2008
Appl. No.:
12/284954
Inventors:
Ake P. Elhammer - Kalamazoo MI, US
Torsten Stachelhaus - Kalamazoo MI, US
International Classification:
A61K 38/12
C07H 21/00
C07K 14/00
A61P 31/04
US Classification:
514 11, 536 231, 530350
Abstract:
The present invention relates to methods of inhibiting the proliferation of bacteria for either ex vivo or in vivo use. The invention also relates to methods of treating a patient infected with an antibiotic resistant bacteria by administering a pharmaceutical composition comprising an Empedopeptin; methods of sanitizing surfaces and instruments; and methods of assaying bacteria for Empedopeptin resistance.

Aureobasin A Synthetase

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US Patent:
20090325155, Dec 31, 2009
Filed:
Aug 25, 2006
Appl. No.:
11/991040
Inventors:
Ake P. Elhammer - Kalamazoo MI, US
Jerry L. Slightom - Pontage MI, US
Brian P. Metzger - Portage MI, US
International Classification:
C12Q 1/68
C12N 15/11
C12N 15/00
C12N 1/15
C12P 21/02
C12N 9/00
US Classification:
435 6, 536 232, 4353201, 43525411, 435 691, 435183
Abstract:
Disclosed are polynucleotides encoding polypeptides having Aureobasidin A synthetase activity and Aureobasidin A synthetase-like activity. The invention also provides methods for detecting AbA synthetase proteins and nucleic acids and AbA synthetase-like proteins and nucleic acids in cells, and method for producing AbA synthetase polypeptides.

Novel Assay For Inositol Phosphorylceramide Synthase Activity

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US Patent:
20100112598, May 6, 2010
Filed:
Dec 18, 2009
Appl. No.:
12/641435
Inventors:
Ake Elhammer - Kalamazoo MI, US
Assignee:
AureoGen Biosciences, Inc. - Kalamazoo MI
International Classification:
G01N 33/573
US Classification:
435 74
Abstract:
Disclosed is a simple and reproducible method for assaying inositol phosphorylceramide synthase activity that employs a fluorescence resonance energy transfer pair for measuring enzyme activity. The invention also includes a novel method for identifying IPC synthase inhibitors.

Aureobasidin Derivatives And Methods Of Synthesis

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US Patent:
20140024578, Jan 23, 2014
Filed:
Mar 23, 2012
Appl. No.:
14/006493
Inventors:
Peter Wuts - Kalamazoo MI, US
Ake P. Elhammer - Kalamazoo MI, US
Assignee:
AureoGen Biosciences ,Inc. - Kalamazoo MI
International Classification:
C07K 1/113
C07K 11/02
US Classification:
514 36, 530323, 514 23, 435184
Abstract:
In general, the invention relates to methods of synthesizing AbA derivatives that are useful for treating infection and amenable to further chemical elaboration. These novel methods are scalable for industrial production and employ safer, simpler, and more efficient process conditions. Furthermore, the invention also provides novel compounds and intermediates useful for implementing the methods described herein and/or for the treatment of infection.

Cloned Dna Encoding A Udp-Galnac: Polypeptide, N-Acetylgalactosaminyltransferase

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US Patent:
60965126, Aug 1, 2000
Filed:
Nov 11, 1997
Appl. No.:
8/967506
Inventors:
Ake P. Elhammer - Kalamazoo MI
Fred L. Homa - Kalamazoo MI
Assignee:
Pharmacia & Upjohn Company - Kalamazoo MI
International Classification:
C12N 1554
C12P 2100
US Classification:
435 681
Abstract:
The present invention relates to a method for the isolation and expression of a glycosyltransferase enzyme for use in the synthesis of oligosaccharide or polysaccharide structures on glycoproteins, glycolipids, or as free molecules. The gene coding for the enzyme N-acetylgalactosaminyltransferase and the polypeptide sequence of the acceptor peptide for the enzyme N-acetylgalactosaminyltransferase have been isolated and used for the control of glycosylation of a protein.

Cloned Dna Encoding A Udp-Galnac: Polypeptide N-Acetylgalactosaminy-Ltransferase

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US Patent:
59105704, Jun 8, 1999
Filed:
Nov 11, 1997
Appl. No.:
8/967508
Inventors:
Ake P. Elhammer - Kalamazoo MI
Fred L. Homa - Kalamazoo MI
Assignee:
Pharmacia & Upjohn Company - Kalamazoo MI
International Classification:
C07K 706
C12N 910
US Classification:
530328
Abstract:
The present invention relates to a method for the isolation and expression of a glycosyltransferase enzyme for use in the synthesis of oligosaccharide or polysaccharide structures on glycoproteins, glycolipids, or as free molecules. The gene coding for the enzyme N-acetylgalactosaminyltransferase and the polypeptide sequence of the acceptor peptide for the enzyme N-acetylgalactosaminyltransferase have been isolated and used for the control of glycosylation of a protein.
Ake P Elhammer from Kalamazoo, MI, age ~76 Get Report