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Ajit Kumar Parhi

from Plainsboro, NJ
Age ~53
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Also known as:
Ajit K Parhi, Ajit Parji
Phone and address:
83 Tennyson Dr, Plainsboro, NJ 08536
(609) 799-7826
Connected to:
Bidyashree Parhi, 56Sima Parhikhteh, 42Barbara D Parhizgar, 71Eugene Parhomovsky, 57Claudia M Pari, 40Kadri L Pari, 48Mason M Pari, 67Mauro E Pari, 98Meena Pari, 50Nancy S Pari, 77

Ajit Parhi Phones & Addresses

  • 83 Tennyson Dr, Plainsboro, NJ 08536 (609) 799-7826
  • Highland Park, NJ
  • Feasterville Trevose, PA
  • 333 North Ave, Clifton Heights, PA 19018 (484) 478-8011
  • Secane, PA
  • State College, PA
  • Ozone Park, NY
  • Elmhurst, NY
  • New York, NY

Publications

Us Patents

Antimicrobial Agents

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US Patent:
20120059026, Mar 8, 2012
Filed:
Apr 30, 2010
Appl. No.:
13/266740
Inventors:
Edmond J. LaVoie - New Brunswick, NJ, US
Daniel S. Pilch - Somerset NJ, US
Ajit Parhi - New Brunswick NJ, US
Malvika Kaul - Somerset NJ, US
Assignee:
University of Medicine and Dentistry of New Jersey - Somerset NJ
Rutgers, The State University of New Jersey - New Brunswick NJ
International Classification:
A61K 31/472
A01N 43/42
A61P 31/04
A61K 31/473
A01P 1/00
C07D 217/02
C07D 221/18
US Classification:
514284, 546144, 514307, 546 73
Abstract:
The invention provides a compound of formula (I): or a salt or prodrug thereof, wherein Y, W, Z, Z, Z, Z, Z, and R-Rhave any of the values described in the specification, as well as compositions comprising a compound of formula (I). The compounds are useful as antibacterial agents.

Topoisomerase Inhibitors

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US Patent:
20120237531, Sep 20, 2012
Filed:
Nov 4, 2010
Appl. No.:
13/318455
Inventors:
Edmond J. LaVoie - New Brunswick NJ, US
Ajit K. Parhi - New Brunswick NJ, US
International Classification:
C07D 491/147
A61P 35/00
A61K 39/395
A61P 31/10
C07K 16/00
A61K 31/4375
US Classification:
4241781, 5303913, 546 48, 514280
Abstract:
The invention provides compounds of formula I: (I) wherein A, B, W, Y, Z, R, Rand Rhave any of the meanings defined in the specification and their salts as well as additional compounds and their salts. The invention also provides pharmaceutical compositions comprising a compound of the invention, processes for preparing compounds of the invention, intermediates useful for preparing compounds of the invention, and therapeutic methods for treating cancer, a bacterial infection or a fungal infection using compounds of the invention.

Antimicrobial Agents

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US Patent:
20130109713, May 2, 2013
Filed:
Jun 24, 2011
Appl. No.:
13/806033
Inventors:
Edmond J. Lavoie - New Brunswick NJ, US
Ajit Parhi - New Brunswick NJ, US
Daniel S. Pilch - Somerset NJ, US
International Classification:
C07D 215/14
C07C 217/80
C07D 239/26
C07D 405/10
C07D 307/52
C07D 491/056
C07D 213/20
US Classification:
514291, 546173, 514311, 546 90, 564287, 546339, 5462834, 549491, 544333, 544335, 564428, 546167, 546 85, 546 61, 514650, 514634, 514643
Abstract:
The invention provides a compound of formula I:or a salt thereof, wherein R-Rand X and Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as antibacterial agents.

Antimicrobial Agents

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US Patent:
20130116278, May 9, 2013
Filed:
Jun 9, 2011
Appl. No.:
13/702936
Inventors:
Edmond J. Lavoie - Princeton Jct. NJ, US
Ajit Parhi - New Brunswick NJ, US
Daniel S. Pilch - Highland Park NJ, US
International Classification:
A61K 31/4709
C07D 401/02
C07D 217/22
A61K 31/47
US Classification:
514309, 546143, 514310, 546141, 546144, 514307
Abstract:
The invention provides a compound of formula (I): or a salt or prodrug thereof, wherein R, R-R, R, R′-R′, W, and A have any of the values described in the specification, as well as compositions comprising a compound of formula (I). The compounds are useful as antibacterial agents.

Benzo [C] Phenanthridines As Antimicrobial Agents

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US Patent:
20120022061, Jan 26, 2012
Filed:
Jan 15, 2010
Appl. No.:
13/144675
Inventors:
Edmond J. LaVoie - New Brunswick NJ, US
Ajit Parhi - New Brunswick NJ, US
Daniel S. Pilch - Somerset NJ, US
Malvika Kaul - Somerset NJ, US
International Classification:
A61K 31/5377
C07D 221/18
C07D 405/10
C07D 413/10
C07D 401/10
A61P 31/04
A61K 31/4355
A61K 31/435
A01N 43/90
A01N 43/42
A01N 43/84
A01P 1/00
C07D 491/056
C07D 491/153
US Classification:
5142328, 546 48, 546 61, 544125, 546 41, 514280, 514284, 514279
Abstract:
The present invention provides compounds of formula I: formula (I) wherein X-Xand R-Rhave any of the values defined in the specification, as well as salts and prodrugs thereof, which inhibit major molecular mechanisms associated with bacterial cell division and proliferation so as to be useful for the treatment and/or prevention of bacterial infections. The invention also provides compositions comprising these compounds as well as methods for using these compounds to inhibit bacterial cell division and proliferation and to treat bacterial infections.

Bacterial Efflux Pump Inhibitors

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US Patent:
20210137881, May 13, 2021
Filed:
Mar 9, 2018
Appl. No.:
16/492908
Inventors:
- New Brunswick NJ, US
Ajit Parhi - New Brunswick NJ, US
Yongzheng Zhang - Monmouth Junction NJ, US
Assignee:
RUTGERS, THE STATE UNIVERISTY OF NEW JERSEY - New Brunswick NJ
International Classification:
A61K 31/40
A61K 45/06
A61P 31/04
C07D 207/14
C07D 207/09
C07D 207/12
A61K 9/20
A61K 9/48
A61K 9/00
A61K 47/02
A61K 9/08
A61K 9/28
Abstract:
Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.

Synthetic Processes And Synthetic Intermediates

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US Patent:
20210139508, May 13, 2021
Filed:
Aug 19, 2020
Appl. No.:
16/997716
Inventors:
- Monmouth Junction NJ, US
Fu-An Kang - Monmouth Junction NJ, US
Nareshkumar Jain - Monmouth Junction NJ, US
Ajit K. Parhi - Monmouth Junction NJ, US
Ravi Ponnaiah - Hyderabad, IN
Anil Kumar Soni - Hyderabad, IN
Siva Rami Reddy Athunuri - Hyderabad, IN
Thrisulapani Korrakuti - Hyderabad, IN
Pullarao Seelam - Hyderabad, IN
Assignee:
TAXIS PHARMACEUTICALS, INC. - Monmouth Junction NJ
International Classification:
C07D 513/04
B01J 23/44
Abstract:
The invention provides synthetic intermediates and synthetic processes that are useful for preparing the antibacterial agent TXA709:

Indole Derivatives As Efflux Pump Inhibitors

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US Patent:
20210094912, Apr 1, 2021
Filed:
Mar 9, 2018
Appl. No.:
16/492901
Inventors:
- New Brunswick NJ, US
Ajit Parhi - New Brunswick NJ, US
Yi Yuan - Monmouth Junction NJ, US
Yongzheng Zhang - Monmouth Junction NJ, US
Yangsheng Sun - Monmouth Junction NJ, US
Assignee:
RUTGERS, THE STATE UNIVERISTY OF NEW JERSEY - New Brunswick NJ
International Classification:
C07D 209/42
C07D 405/04
C07D 403/12
C07D 401/12
C07D 401/14
Abstract:
Disclosed herein are compounds of formula (I): and salts thereof. Also disclosed are compositions comprising compounds of formula I and compounds of formula I for use in treating or preventing bacterial infections.
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Ajit Kumar Parhi from Plainsboro, NJ, age ~53 Get Report