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Aine Matthew Quimby

from Newburyport, MA
Age ~40
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Also known as:
Aine B Quimby, Aine D Quimby, Aine D Blanchard, Blanchard Aine
Related to:
Amanda M Quimby, 40
Connected to:
Allen H Quimby, 83Bart C Quimby, 50Brad Quimby, 44Brandi Quimby, 35Christie Quimby, 42Corinna B Quimby, 59Dale A Quimby, 51Danny Quimby, 102Darryl L Quimby, 81Dean L Quimby, 66

Aine Quimby Phones & Addresses

  • Newburyport, MA
  • Newton, NH
  • Sarasota, FL
  • Worcester, MA
  • Hampstead, NH

Work

Company: Abclonal technology Aug 2019 Position: Head associate

Education

Degree: Bachelors, Bachelor of Science School / High School: Worcester Polytechnic Institute 2003 to 2006 Specialities: Biotechnology

Skills

Protein Purification • Protein Expression • Molecular Cloning • Pcr • Gel Electrophoresis • Dna Sequencing • Dna Extraction • Dna • High Throughput Screening • Cell Culture • Western Blotting • Site Directed Mutagenesis • Laboratory Techniques • Molecular Biology • Protein Engineering • Biotechnology • Enzyme Assays • Bacterial Transformation • Capillary Electrophoresis • Mutagenesis • Restriction Enzymes • Vector Cloning • Akta • Competent Cell Preparation

Languages

French

Interests

Cooking • Oil Painting • Gardening • Outdoor Activities • Reading • Hiking • Pets • Animal Welfare • Bicycling

Industries

Biotechnology

Resumes

Resumes

Aine Quimby Photo 1

Head Associate

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Location:
43 Frances Dr, Newburyport, MA 01950
Industry:
Biotechnology
Work:
Abclonal Technology
Head Associate
New England Biolabs Jan 2007 - Apr 2019
Assistant Scientist
Welgen Jun 2006 - Dec 2006
Laboratory Assistant
New World Laboratories May 2005 - Aug 2005
Summer Internship
Therion Biologics May 2004 - Aug 2004
Summer Internship
Education:
Worcester Polytechnic Institute 2003 - 2006
Bachelors, Bachelor of Science, Biotechnology Pinkerton Academy 1999 - 2003
Skills:
Protein Purification
Protein Expression
Molecular Cloning
Pcr
Gel Electrophoresis
Dna Sequencing
Dna Extraction
Dna
High Throughput Screening
Cell Culture
Western Blotting
Site Directed Mutagenesis
Laboratory Techniques
Molecular Biology
Protein Engineering
Biotechnology
Enzyme Assays
Bacterial Transformation
Capillary Electrophoresis
Mutagenesis
Restriction Enzymes
Vector Cloning
Akta
Competent Cell Preparation
Interests:
Cooking
Oil Painting
Gardening
Outdoor Activities
Reading
Hiking
Pets
Animal Welfare
Bicycling
Languages:
French

Publications

Us Patents

High Fidelity Restriction Endonucleases

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US Patent:
8637291, Jan 28, 2014
Filed:
Feb 7, 2011
Appl. No.:
13/022561
Inventors:
Zhenyu Zhu - Beverly MA, US
Aine Quimby - Newton NH, US
Shengxi Guan - Stoneham MA, US
Dapeng Sun - Arlington MA, US
Yishu Huang - Shanghai, CN
Xuhui Lai - Shanghai, CN
Siu-hong Chan - Ipswich MA, US
Xianghui Li - Shanghai, CN
Chunhua Zhang - Zhenjiang, CN
Assignee:
New England Biolabs, Inc. - Ipswich MA
International Classification:
C12N 9/22
US Classification:
435199, 536 232
Abstract:
Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) in a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer.

Engineering A Novel Methylation-Specific Restriction Endonuclease

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US Patent:
20120088237, Apr 12, 2012
Filed:
Mar 4, 2010
Appl. No.:
13/202851
Inventors:
Zhenyu Zhu - Beverly MA, US
Shengxi Guan - Stoneham MA, US
Aine Quimby - Newton NH, US
Assignee:
NEW ENGLAND BIOLABS, INC. - Ipswich MA
International Classification:
C12Q 1/68
C12N 9/16
C12N 1/21
C12N 15/55
C12N 15/63
US Classification:
435 611, 536 232, 4353201, 43525233, 435196, 435 61
Abstract:
A restriction endonuclease is provided that has been engineered to have a cleavage specificity for a DNA recognition sequence containing a modified nucleotide. Methods for engineering enzymes to cleave DNA containing modified nucleotides at specific sequences are provided.

Compositions, Methods And Related Uses For Cleaving Modified Dna

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US Patent:
20120301881, Nov 29, 2012
Filed:
Jan 20, 2011
Appl. No.:
13/522224
Inventors:
Zhenyu Zhu - Beverly MA, US
Yu Zheng - Topsfield MA, US
Shengxi Guan - Stoneham MA, US
Hua Wang - Topsfield MA, US
Aine Quimby - Newton NH, US
Penghua Zhang - Lexington MA, US
Lynne Apone - Waltham MA, US
Assignee:
NEW ENGLAND BIOLABS, INC. - Ipswich MA
International Classification:
C12Q 1/68
C12N 9/16
US Classification:
435 611, 435196
Abstract:
Compositions, methods and a kit are described relating to a novel family of enzymes which preferentially bind to a hydroxymethylated cytosine or a glucosylated hydroxymethylated cytosine and cleave double-stranded DNA at a defined distance 3′ of the recognition site to produce a cleavage fragment with a 1-3 base overhang.

High Fidelity Restriction Endonucleases

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US Patent:
20130115676, May 9, 2013
Filed:
Jan 8, 2013
Appl. No.:
13/736296
Inventors:
Aine Quimby - Newton NH, US
Shengxi Guan - Stoneham MA, US
Hua Wei - Ipswich MA, US
Penghua Zhang - Lexington MA, US
Dapeng Sun - Arlington MA, US
Siu-hong Chan - Ipswich MA, US
Assignee:
NEW ENGLAND BIOLABS, INC. - Ipswich MA
International Classification:
C12N 9/22
US Classification:
435196, 536 232, 4353201, 43525233, 506 11
Abstract:
Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.

High Fidelity Restriction Endonucleases

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US Patent:
20130115677, May 9, 2013
Filed:
Jan 8, 2013
Appl. No.:
13/736406
Inventors:
Aine Quimby - Newton NH, US
Shengxi Guan - Stoneham MA, US
Hua Wei - Ipswich MA, US
Penghua Zhang - Lexington MA, US
Dapeng Sun - Arlington MA, US
Siu-hong Chan - Ipswich MA, US
Assignee:
NEW ENGLAND BIOLABS, INC. - Ipswich MA
International Classification:
C12N 9/22
US Classification:
435196, 536 232, 4353201, 43525233, 506 11
Abstract:
Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.

High Fidelity Restriction Endonucleases

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US Patent:
20130115678, May 9, 2013
Filed:
Jan 8, 2013
Appl. No.:
13/736561
Inventors:
Aine Quimby - Newton NH, US
Shengxi Guan - Stoneham MA, US
Hua Wei - Ipswich MA, US
Penghua Zhang - Lexington MA, US
Dapeng Sun - Arlington MA, US
Siu-hong Chan - Ipswich MA, US
Assignee:
NEW ENGLAND BIOLABS, INC. - Ipswich MA
International Classification:
C12N 9/22
US Classification:
435196, 536 232, 4353201, 43525233, 506 11
Abstract:
Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.

High Fidelity Restriction Endonucleases

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US Patent:
20130115679, May 9, 2013
Filed:
Jan 8, 2013
Appl. No.:
13/736598
Inventors:
Aine Quimby - Newton NH, US
Shengxi Guan - Stoneham MA, US
Hua Wei - Ipswich MA, US
Penghua Zhang - Lexington MA, US
Dapeng Sun - Arlington MA, US
Siu-hong Chan - Ipswich MA, US
Assignee:
NEW ENGLAND BIOLABS, INC. - Ipswich MA
International Classification:
C12N 9/22
US Classification:
435196, 536 232, 4353201, 43525233, 506 11
Abstract:
Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.

High Fidelity Restriction Endonucleases

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US Patent:
20130115680, May 9, 2013
Filed:
Jan 8, 2013
Appl. No.:
13/736170
Inventors:
Aine Quimby - Newton NH, US
Shengxi Guan - Stoneham MA, US
Hua Wei - Ipswich MA, US
Penghua Zhang - Lexington MA, US
Dapeng Sun - Arlington MA, US
Siu-hong Chan - Ipswich MA, US
Assignee:
NEW ENGLAND BIOLABS, INC. - Ipswich MA
International Classification:
C12N 9/22
US Classification:
435199, 536 232, 4353201, 506 2, 43525233
Abstract:
Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.
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Aine Matthew Quimby from Newburyport, MA, age ~40 Get Report