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Aesop Te Cho

from Mountain View, CA
Age ~67

Aesop Cho Phones & Addresses

  • 1656 Notre Dame Dr, Mountain View, CA 94040
  • Santa Clara, CA

Publications

Us Patents

Fungal Efflux Pump Inhibitors

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US Patent:
6689782, Feb 10, 2004
Filed:
Dec 30, 2002
Appl. No.:
10/334755
Inventors:
William J. Watkins - Sunnyvale CA
Remy Lemoine - San Francisco CA
Aesop Cho - Mountain View CA
Monica Palme - San Jose CA
Assignee:
Essential Therapeutics, Inc. - Waltham MA
International Classification:
A61K 31495
US Classification:
51425217, 514183, 5142661, 5142662, 5142663, 544287, 544322, 544253, 544283, 544358, 544359
Abstract:
This invention relates to compounds that are efflux pump inhibitors and therefore are useful as potentiators of anti-fungal agents for the treatment of infections caused by fungi that employ an efflux pump resistance mechanism.

7-Acylamino-3-Heteroarylthio-3-Cephem Carboxylic Acid Antibiotics And Prodrugs Thereof

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US Patent:
6723716, Apr 20, 2004
Filed:
Sep 21, 2000
Appl. No.:
09/668722
Inventors:
Scott J. Hecker - Los Gatos CA
Aesop Cho - Mountain View CA
Tomasz W. Glinka - Sunnyvale CA
Trevor Calkins - Londonderry NH
Ving J. Lee - Los Altos CA
Assignee:
Essential Therapeutics, Inc. - Waltham MA
International Classification:
C07D50159
US Classification:
514203, 514204, 540224, 540225, 540226, 540227
Abstract:
The present invention relates to a cephem prodrug having formula III or formula IV: or a pharmaceutically acceptable salt thereof, wherein Râ is selected from the group consisting of hydrogen and âC(O)CH(NH )CH and Râ is selected from the group consisting of hydrogen and an acyl group that is cleaved by an enzyme found in mammals, with the proviso that, when either Râ or Râ is hydrogen, the other is not. A, B, L, G, E, and J are each independently nitrogen or carbon such that the respective rings are selected from the group consisting of provided that the group âCH âSâCH CH NHRâ is attached only to a carbon atom of said heterocyclic group, and Q is selected from the group consisting of nitrogen and âCX, wherein X is selected from the group consisting of hydrogen and chlorine.

Drug Efflux Pump Inhibitor

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US Patent:
7056917, Jun 6, 2006
Filed:
Apr 26, 2001
Appl. No.:
09/842234
Inventors:
Kiyoshi Nakayama - Funabashi, JP
Masami Ohtsuka - Tokyo, JP
Haruko Kawato - Tokyo, JP
William Watkins - Sunnyvale CA, US
Jason Zhang - Foster City CA, US
Monica Palme - San Jose CA, US
Aesop Cho - Mountain View CA, US
Assignee:
Daiichi Pharmaceutical Co., Ltd. - Tokyo
Trine Pharmaceuticals, Inc. - Waltham MA
International Classification:
C07D 417/06
C07D 417/12
A61K 31/427
US Classification:
5142332, 514248, 514258, 514300, 514312, 544116, 544235, 544236, 544282, 546122, 546153, 546155, 546156
Abstract:
A medicament for preventive and/or therapeutic treatment of a microbial infection which comprises as an active ingredient a compound represented by the following general formula (I): wherein, Rand Rrepresent hydrogen atom, a halogen atom, hydroxyl group or the like, Wrepresents —CH═CH—, —CHO—, —CHCH— or the like; Rrepresents hydrogen atom, a halogen atom, hydroxyl group or an amino group; Rrepresents hydrogen atom, a group of —OZR(Zrepresents an alkylene group, a fluorine-substituted alkylene group or a single bond, and Rrepresents a cyclic alkyl group, an aryl group or the like); Wrepresents a single bond or —C(R)═C(R)— (Rand Rrepresent hydrogen atom, a halogen atom, a lower alkyl group or the like, Q represents an acidic group, but Wand Q may together form vinylidenethiazolidinedione or an equivalent heterocyclic ring; m and n represent an integer of 0 to 2, and q represents an integer of 0 to 3.

Anti-Infective Phosphonate Analogs

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US Patent:
7300924, Nov 27, 2007
Filed:
Apr 26, 2004
Appl. No.:
10/833291
Inventors:
Constantine G. Boojamra - San Francisco CA, US
Aesop Cho - Mountain View CA, US
William J. Watkins - Sunnyvale CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/675
C07D 267/22
US Classification:
514 80, 514 81, 540458
Abstract:
The invention is related to phosphorus substituted anti-infective compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Phosphonate Analogs For Treating Metabolic Diseases

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US Patent:
7407965, Aug 5, 2008
Filed:
Apr 26, 2004
Appl. No.:
10/832817
Inventors:
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee S. Chong - Newark CA, US
Maria Fardis - San Carlos CA, US
Thorsten Kirschberg - Belmont CA, US
Steven Krawczyk - San Carlos CA, US
Hyung-Jung Pyun - Freemont CA, US
William J. Watkins - Sunnyvale CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/505
C07F 9/02
US Classification:
514275, 544243
Abstract:
The invention is related to phosphorus substituted compounds with activity for treating metabolic diseases and/or disorders, e. g. , diabetes and hypercholesterolemia, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Kinase Inhibitory Phosphonate Analogs

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US Patent:
7417055, Aug 26, 2008
Filed:
Apr 26, 2004
Appl. No.:
10/832811
Inventors:
Carina Cannizzaro - San Mateo CA, US
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee S. Chong - Newark CA, US
Manoj Desai - Pleasant Hill CA, US
Maria Fardis - San Carlos CA, US
Thorsten Kirschberg - Belmont CA, US
Richard L. Mackman - Millbrae CA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
William J. Watkins - Sunnyvale CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/44
C07D 239/72
US Classification:
514306, 544293
Abstract:
The invention is related to phosphorus substituted kinase inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Purine Nucleoside Phosphorylase Inhibitory Phosphonate Compounds

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US Patent:
7427624, Sep 23, 2008
Filed:
Apr 26, 2004
Appl. No.:
10/832816
Inventors:
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee S. Chong - Newark CA, US
Maria Fardis - San Carlos CA, US
Thorsten Kirschberg - Belmont CA, US
Adrian S. Ray - San Mateo CA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
William J. Watkins - Sunnyvale CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/517
C07D 487/00
US Classification:
5142661, 544280, 544232
Abstract:
The invention is related to phosphorus substituted purine nucleoside phosphorylase inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Inosine Monophosphate Dehydrogenase Inhibitory Phosphonate Compounds

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US Patent:
7427636, Sep 23, 2008
Filed:
Apr 26, 2004
Appl. No.:
10/832829
Inventors:
Carina Cannizzaro - San Mateo CA, US
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee S. Chong - Newark CA, US
Maria Fardis - San Carlos CA, US
Thorsten Kirschberg - Belmont CA, US
Hyung-Jung Pyun - Freemont CA, US
William J. Watkins - Sunnyvale CA, US
Jennifer R. Zhang - Foster City CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/42
C07D 263/30
US Classification:
514374, 514 79, 548235, 548112
Abstract:
The invention is related to phosphorus substituted IMPDH inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
Aesop Te Cho from Mountain View, CA, age ~67 Get Report