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Adrien P Malick

from Granite, MD
Age ~65
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Also known as:
Adrien Paul Malick, Adrien P Marick, Adrien Malich
Phone and address:
10817 Acme Ave, Woodstock, MD 21163
(410) 465-8901
Related to:
Laurie L Longo, 38Chii Chwang, 74Norine Chwang, 46Emily Chwang, 43Mary J Chwang, 38Sevren Chwang, 35
Connected to:
Alston Malicka, 38Kacer S Malick, 32Khouma Malick, 68Marissa E Malick, 43Mohammad Malick, 41Nancy A Malick, 82Shawna Malick, 43Traore Malick, 64Alex Malicki, 33Brandon A Malicki, 38

Adrien Malick Phones & Addresses

  • 10817 Acme Ave, Woodstock, MD 21163 (410) 465-8901
  • Granite, MD
  • Baltimore, MD
  • Blacksburg, VA
  • Randallstown, MD

Work

Company: Becton dickinson Position: R&d manager

Education

Degree: Ph.D. School / High School: Virginia Polytechnic Institute and State University 1982 to 1987 Specialities: Immunology and Microbiology

Skills

R&D • Immunoassays • Product Development • Technology Evaluation • Project Management • People Management • In Vitro Diagnostics

Emails

a***[email protected]

Industries

Biotechnology

Resumes

Resumes

Adrien Malick Photo 1

Associate Director, Analytical Development

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Location:
Baltimore, MD
Industry:
Biotechnology
Work:
Becton Dickinson
R&D Manager
Education:
Virginia Polytechnic Institute and State University 1982 - 1987
Ph.D., Immunology and Microbiology Loyola College in Maryland 1976 - 1980
BS, Biology
Skills:
R&D
Immunoassays
Product Development
Technology Evaluation
Project Management
People Management
In Vitro Diagnostics

Publications

Us Patents

Method For Direct And Rapid Identification Of Microorganisms And Antimicrobial Susceptibility Testing From Positive Blood Cultures

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US Patent:
8603769, Dec 10, 2013
Filed:
Oct 8, 2012
Appl. No.:
13/647072
Inventors:
William B. Brasso - Columbia MD, US
Song Shi - Reisterstown MD, US
Ben Turng - Ellicott City MD, US
Susan M. Kircher - Hanover PA, US
Vanda White - Baltimore MD, US
Dyan Luper - Cockeysville MD, US
Julie Rosales - Randallstown MD, US
Gretta Campbell - Glen Rock PA, US
Adrien Malick - Granite MD, US
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
C12Q 1/04
C12Q 1/24
US Classification:
435 30, 4352524, 435 34
Abstract:
Methods of the invention include the isolation of intact, viable microorganism(s) from positive blood culture (“PBC”) samples for use in downstream analyses such as identification and antimicrobial susceptibility testing (“AST”). The methods involve collecting a portion of the PBC sample, adding a choline-containing solution, lysing the blood cells, isolating the viable microorganism, and performing downstream analysis of the isolated, viable microorganism. The methods can be applied to a variety of gram-positive bacteria, gram-negative bacteria, and/or yeast, and particularly to strains of.

Method Of Efficient Extraction Of Protein From Cells

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US Patent:
20090123910, May 14, 2009
Filed:
Nov 14, 2007
Appl. No.:
11/985547
Inventors:
Adrien P. Malick - Granite MD, US
Virginia M. Crews - Baltimore MD, US
Julie L. Rosales - Randallstown MD, US
Carrie S. Ferguson - Bel Air MD, US
Jeff H. Bruton - Randallstown MD, US
Robert J. Beadenkopf - Pasadena MD, US
International Classification:
C12Q 1/70
C12P 21/00
G01N 33/50
C12Q 1/00
G01N 33/567
US Classification:
435 5, 435 701, 435 703, 435 405, 435 4, 435 792, 435 721
Abstract:
Methods for producing a protein extract from cells, such as cells or cellular samples containing viral proteins, are provided. In general terms, the methods may involve: increasing the pH of the cells to a pH of at least about pH 10.0 to produce an intermediate composition, and then, in the presence of a non-ionic detergent such as a polyoxyethylene alkyl ether, neutralizing the pH of the intermediate composition to produce the protein extract. Such methods can be used in conjunction with methods for detecting one or more target proteins in a sample, such as viral proteins. Systems, kits and compositions for practicing the subject methods are also provided.

Non-Instrumented Assay With Quantitative And Qualitative Results

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US Patent:
61942200, Feb 27, 2001
Filed:
Sep 25, 1996
Appl. No.:
8/719220
Inventors:
Adrien Paul Malick - Granite MD
Edward Charles McFarland - Parkville MD
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
G01N 33558
G01N 33544
G01N 33543
C12Q 100
US Classification:
436514
Abstract:
The present invention is directed to non-instrumented assays giving quantitative and/or qualitative results. In one embodiment, the present invention is directed to a process and kit determining analyte in a sample wherein the solid support has a contact zone and binder distributed and immobilized throughout the solid support. A sample and a tracer are added to the contact zone and a visible zone is obtained. In another embodiment, the present invention is directed to a process and test wherein the solid support has two contact zones and the binder is not immobilized on the solid support. In this embodiment, the binder is mobile and is added to the second contact zone. At the same time, sample and a tracer are added to the first contact zone. A visible zone is obtained.

Stabilized Microspheres And Methods Of Preparation

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US Patent:
56209037, Apr 15, 1997
Filed:
Jan 18, 1995
Appl. No.:
8/374001
Inventors:
Adrien Malick - Granite MD
Hans H. Feindt - Parkton MD
Gerald D. Hahn - Severn MD
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
G01N 33546
G01N 33543
G01N 33544
G01N 33536
US Classification:
436533
Abstract:
Stabilized microspherical particles having hydrophobic liquid cores prepared as oil-in-water microemulsions. The particles are stabilized by a surface layer comprising an amphiphilic compound and may be functionalized to allow covalent coupling of a ligand to the surface of the particle. When used as tracers in assays, a water insoluble dye may be incorporated in the core liquid of the microparticles.

Stabilized Microspheres And Methods Of Preparation

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US Patent:
56886977, Nov 18, 1997
Filed:
May 3, 1996
Appl. No.:
8/642373
Inventors:
Adrien Malick - Granite MD
Hans H. Feindt - Parkton MD
Gerald D. Hahn - Severn MD
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
G01N 33531
C12Q 100
A61K 3706
US Classification:
436518
Abstract:
Stabilized microspherical particles having hydrophobic liquid cores prepared as oil-in-water microemulsions. The particles are stabilized by a surface layer comprising an amphiphilic compound and may be functionalized to allow covalent coupling of a ligand to the surface of the particle. When used as tracers in assays, a water insoluble dye may be incorporated in the core liquid of the microparticles.

Stabilized Microspheres And Methods Of Preparation

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US Patent:
55938434, Jan 14, 1997
Filed:
Nov 22, 1994
Appl. No.:
8/343795
Inventors:
Adrien Malick - Granite MD
Hans H. Feindt - Parkton MD
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
G01N 3353
G01N 33567
G01N 33537
G01N 33543
US Classification:
435 71
Abstract:
Stabilized microspherical particles having hydrophobic liquid cores prepared as oil-in-water microemulsions. The particles are stabilized by a surface layer comprising an amphiphilic compound and may be functionalized to allow covalent coupling of a ligand to the surface of the particle. When used as tracers in assays, a water insoluble dye may be incorporated in the core liquid of the microparticles.

Assay Of Blood Or Other Biologic Samples For Target Analytes

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US Patent:
56353626, Jun 3, 1997
Filed:
May 23, 1994
Appl. No.:
8/247336
Inventors:
Robert A. Levine - Guilford CT
Stephen C. Wardlaw - Old Saybrook CT
Rodolfo R. Rodriguez - Owings Mills MD
Adrien P. Malick - Granite MD
Alvydas J. Ozinskas - Dayton MD
Assignee:
Becton Dickinson and Co. - Franklin Lakes NJ
International Classification:
G01N 33543
G01N 33558
US Classification:
435 724
Abstract:
A patient's health may be diagnosed by centrifuging blood samples in a transparent tube, which tube contains one or more bodies or groups of bodies such as floats, inserts, liposomes, or plastic beads of different densities. Each density-defined body carries analyte-capture binding materials such as antigens or antibodies, which are specific to an epitope, or other specific high affinity binding site on a target analyte which target analyte may be in the blood or other sample being tested; and the level of which analyte is indicative of the patient's health. At least one labeled binding material which is also specific to an epitope, or other specific high affinity binding site on the target analyte is added to the sample so as to form labeled binding material/analyte/body complexes in the sample. Upon centrifugation, the complexes will settle out in different areas in the tube according to the respective density of the body or bodies; and the degree of label emission of the complex layers can enable qualitative and/or quantitative analyses of the sample to be made. Unbound labeled binding materials will be separated from the complexed layers by the washing action of ascending or descending components of the sample during the centrifugation step.

Assay Of Blood Or Other Biologic Samples For Target Analytes

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US Patent:
58342176, Nov 10, 1998
Filed:
Dec 11, 1996
Appl. No.:
8/763858
Inventors:
Robert A. Levine - Guilford CT
Stephen C. Wardlaw - Old Saybrook CT
Leon W. M. M. Terstappen - Palo Alto CA
Kristen L. Manion - Benecia CA
Rodolfo R. Rodriguez - Owings Mills MD
Adrien P. Malick - Granite MD
Subhash Dhanesar - Owings Mills MD
Stephen J. Lovell - Baltimore MD
Alvydas J. Ozinskas - Dayton MD
Assignee:
Becton Dickinson and Co. - Franklin Lakes NJ
International Classification:
G01N 33543
G01N 33546
US Classification:
435 724
Abstract:
A patient's health may be diagnosed by centrifuging blood samples in a transparent tube, which tube contains one or more bodies or groups of bodies such as floats, inserts, liposomes, or plastic beads of different densities. Each density-defined body carries analyte-capture binding materials such as antigens or antibodies, which are specific to an epitope, or other specific high affinity binding site on a target analyte which target analyte may be in the blood or other sample being tested; and the level of which analyte is indicative of the patient's health. At least one labeled binding material which is also specific to an epitope, or other specific high affinity binding site on the target analyte is added to the sample so as to form labeled binding material/analyte/body complexes in the sample. Upon centrifugation, the complexes will settle out in different areas in the tube according to the respective density of the body or bodies; and the degree of label emission of the complex layers can enable qualitative and/or quantitative analyses of the sample to be made. Unbound labeled binding materials will be separated from the complexed layers by the washing action of ascending or descending components of the sample during the centrifugation step.
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Adrien P Malick from Granite, MD, age ~65 Get Report