S Chin Phones & Addresses
-
San Jose, CA
Publications
Us Patents
Characterization Of The Gsk-3Beta Protein And Methods Of Use Thereof
View pageUS Patent:
20040101907, May 27, 2004
Filed:
Dec 11, 2003
Appl. No.:
10/450422
Inventors:
Dirksen Bussiere - San Leandro CA, US
Min He - Union City CA, US
Vincent P Le - San Francisco CA, US
Johanna Jansen - San Francisco CA, US
S Chin - Albany CA, US
Eric Martin - El Cerrito CA, US
Min He - Union City CA, US
Vincent P Le - San Francisco CA, US
Johanna Jansen - San Francisco CA, US
S Chin - Albany CA, US
Eric Martin - El Cerrito CA, US
International Classification:
G01N033/53
G06F019/00
G01N033/48
G01N033/50
G06F019/00
G01N033/48
G01N033/50
US Classification:
435/007100, 702/019000
Abstract:
The invention provides the three-dimensional structure of a construct of human glycogen synthase kinase 3 (GSK3); crystals of a construct of human glycogen synthase kinase 3- (GSK3-); containing the protein's catalytic kinase domain; a domain for crystallizing the protein construct to provide a GSK3 crystal sufficient for structure determination; and a method for using the GSK3 construct's three dimensional structure for the identification of possible therapeutic compounds in the treatment of various disease conditions mediated by GSK3 activity.