Jian Fu Chen

7034134, Apr 25, 2006

Apr 26, 2002

10/133797

Shujian Wu - Langhorne PA, US
Jian Chen - Princeton NJ, US

Bristol-Myers Squibb Company - Princeton NJ

C07H 21/00
C07K 14/47

536 232, 435212, 435 691, 530400

The present invention provides novel polynucleotides encoding MMP-29 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MMP-29 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

7073830, Jul 11, 2006

Oct 25, 2005

11/258303

Jian Chen - Flushing NY, US
Dennis Q. Chen - Flushing NY, US

B60R 19/44

293142, 293109, 293126

A bumper protection device for automobile bumpers to shield the bumpers from impact attaches to the automobile by a fabric shroud which attaches around the hood and trunk latch and suspends an impact resisting padded guard portion, adapted to the vehicle bumper, covering the entire front or rear bumper, the padded guard portion being drawn partially around the sides of the bumper and anchored by at least one elastic strap attached to opposing ends of the bumper guard portion, each elastic strap being further attached to the tires or wheel wells of the automobile retaining the bumper protection device over the entire rear bumper surface and around the sides of the bumper.

7285633, Oct 23, 2007

Dec 21, 2005

11/313356

Shujian Wu - Langhorne PA, US
Jian Chen - Princeton NJ, US
John N. Feder - Belle Mead NJ, US
Liana Lee - North Brunswick NJ, US
Stanley R. Krystek - Ringoes NJ, US

Bristol-Myers Squibb Company - Princeton NJ

A61K 38/17

530350

The present invention provides novel polynucleotides encoding MMP-29 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MMP-29 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

8420829, Apr 16, 2013

Apr 5, 2011

13/079888

Jian Chen - West Chester PA, US
Katrin Przyuski - Phoenixville PA, US
Renee Caroline Roemmele - Maple Glen PA, US

Cephalon, Inc. - Frazer PA

C07D 235/16

5483101

New methods for the preparation of bendamustine, and the pharmaceutical salts thereof, are described. Novel compounds useful for the preparation of bendamustine are also described.

20040014093, Jan 22, 2004

Mar 14, 2003

10/390585

Franck Duclos - Washington Crossing PA, US
Jian Chen - Princeton NJ, US
John Feder - Belle Mead NJ, US
Akbar Nayeem - Newtown PA, US
Thomas Nelson - Lawrenceville NJ, US

C12Q001/68
G06F019/00
G01N033/48
G01N033/50
C07H021/04
C12N009/64
C12P021/02
C12N005/06

435/006000, 435/069100, 435/226000, 435/320100, 435/325000, 536/023200, 702/019000

The present invention provides novel polynucleotides encoding Protease-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel Protease-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

20130052711, Feb 28, 2013

Aug 24, 2012

13/594730

Jian Chen - Blue Bell PA, US

C12M 1/42
C12N 13/00

4351736, 4352852

An apparatus for electroporation of biological cells is provided. The apparatus includes a sample container having an insulator chamber for holding the cells. The sample container has a first electrode and a second electrode to provide electrical connection for electroporation. The insulator chamber is configured to contain at least one cell monolayer. The apparatus also includes a pulse generator that can generate a predetermined pulse for electroporation of the cells.

54950520, Feb 27, 1996

Sep 29, 1994

8/314843

Wilfred P. Shum - West Chester PA
Harry Mazurek - Bala Cynwyd PA
Jian Chen - West Chester PA

Arco Chemical Technology, L.P. - Greenville DE

C07C 4103
C07C 43205

568648

A tertiary amine is used to catalize the stereospecific ring-opening of chiral glycidol with o-methoxyphenol to afford high yields of enantiomerically enriched guaifenesin. The optical purity of the product may be even further enhanced by recrystallization.

20210371797, Dec 2, 2021

Aug 17, 2021

17/404753

JIAN CHEN - Blue Bell PA, US

C12M 1/42
C12N 13/00
C12N 15/87

An apparatus for electroporation of biological cells is provided. The apparatus includes a sample container having an insulator chamber for holding the cells. The sample container has a first electrode and a second electrode to provide electrical connection for electroporation. The insulator chamber is configured to contain at least one cell monolayer. The apparatus also includes a pulse generator that can generate a predetermined pulse for electroporation of the cells.