Guangyang Wang Phones & Addresses
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13200 Foxden Dr, Rockville, MD 20850
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Leesburg, VA
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Germantown, MD
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Ashburn, VA
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Frederick, MD
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Gaithersburg, MD
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Boyds, MD
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Pasadena, CA
Education
Degree:
Graduate or professional degree
Publications
Us Patents
Hexahydrofuro[2,3-B]Furan-3-Yl-N-{3-[(1,3-Benzodioxol-5-Ylsulfonyl)(Isobutyl)Amino]-1-Benzyl-2-Hydroxypropyl}Carbamate As Retroviral Protease Inhibitor
View pageUS Patent:
20050261364, Nov 24, 2005
Filed:
Jun 25, 2003
Appl. No.:
10/606342
Inventors:
Guangyang Wang - Gaithersburg MD, US
Michael Eissenstat - Frederick MD, US
John Erickson - Frederick MD, US
Piet Wigerinck - Vosselaar, BE
Michael Eissenstat - Frederick MD, US
John Erickson - Frederick MD, US
Piet Wigerinck - Vosselaar, BE
International Classification:
A61K031/36
C07D047/02
C07D047/02
US Classification:
514464000, 549435000
Abstract:
Compositions comprising bis-tetrahydrofuran benzodioxyolyl sulfonamide compounds that are surprisingly effective protease inhibitors and a second antiretroviral compound are disclosed. Methods of inhibiting retrovirus proteases, in particular multi-drug resistant retrovirus proteases, methods of treating or preventing infection or disease associated with retrovirus infection in a mammal, and methods of inhibiting viral replication are also disclosed.